Results 71 to 80 of about 4,571,560 (259)

Blood pressure measures and their predictive ability of cardiovascular mortality : a 26-year follow-up

open access: yes, 2013
Objective(s) Our aim was to calculate the predictability of different blood pressure measures for cardiovascular mortality in a cohort of both men and women.
Carlsson, Axel C.,   +7 more
core   +1 more source

A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy

open access: yesAdvanced Science, EarlyView.
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu   +17 more
wiley   +1 more source

Palpatory method of measuring diastolic blood pressure

open access: yesJournal of Anaesthesiology Clinical Pharmacology, 2010
Background: Most common method for measuring blood pressure is palpatory but only systolic pressure can be measured with this method. In this study we are describing palpatory method of measuring diastolic blood pressure as well.
Dinesh Sahu, M Bhaskaran
doaj  

Printable Piezoresistive Hybrid Hydrogels Based on 2D MoS2 for Flexible Pulse Sensing

open access: yesAdvanced Science, EarlyView.
Hybrid 1T‐MoS2‐based hydrogels are engineered through UV curing and 3D printing to achieve tunable electromechanical properties for wearable sensing. These soft architectures enhance mechanical stability and reproducible piezoresistive responses within the physiological pressure range.
Jenny Flores   +18 more
wiley   +1 more source

Low Diastolic Blood Pressure and High Blood Pressure Variability are Risk Factors for Cognitive Decline in Elderly Adults: A Case-Control Study [PDF]

open access: yes, 2019
Background This study investigated the association between visit-to-visit blood pressure (BP) variability and cognitive decline in elderly adults over a 4-month period. Methods All 94 elderly volunteers were recruited from a community center.
Chen, Chia-Chi;Lee, Jia-Fu;Ko, Yu-Lin;Lee, Chun-Te;Chang, Yue-Cune
core   +1 more source

Glomerular hyperfiltration is associated with blood pressure abnormalities in normotensive normoalbuminuric IDDM patients

open access: yesClinical and Biomedical Research, 2022
OBJECTIVE: To analyze the blood pressure patterns in normoalbuminuric IDDM patients with glomerular hyperfiltration. PATIENTS AND METHODS: A controlled cross-sectional study of 38 normotensive normoalbuminuric (urinary albumin excretion rate 134 ml ...
Miriam Pecis   +2 more
doaj  

Metabolic Memory in Cardiovascular Disease: Encoding, Propagation, and Therapeutic Targeting

open access: yesAdvanced Science, EarlyView.
Cardiovascular risk often persists after metabolic abnormalities are corrected. This conceptual Review frames such persistence as metabolic memory, encoded through a narrowing therapeutic window from reversible marks to irreversible damage, with continuous input from peripheral organs.
Cheng Cheng   +12 more
wiley   +1 more source

Increased Disarray of Extracellular Matrix Collagen‐I Fiber Network and Compromised Biomechanics in Aortae From Marfan‐Syndrome Mice Assessed Through Combined Opto‐Biomechatronics

open access: yesAdvanced Science, EarlyView.
Combined structure‐function assessment in aortic rings from Marfan mice using MechaMorph Opto‐Biomechatronics technology relates increased elasticity (stiffness) and dynamic viscosity and less ordered extracellular matrix 3D‐structure (collagen) as potential causes for impaired Windkessel function and compromised haemodynamics in Marfan's syndrome ...
Dominik Schneidereit   +10 more
wiley   +1 more source

Gut Microbiota‐Derived Indole‐3‐Propionic Acid Alleviates Diabetic Osteoporosis Through Nrf2‐Mediated Ferroptosis Suppression

open access: yesAdvanced Science, EarlyView.
Diabetes‐associated dysbiosis is accompanied by reduced Clostridium abundance, impaired microbial tryptophan metabolism, and lower circulating indole‐3‐propionic acid (IPA). Exogenous IPA improves trabecular microarchitecture and bone formation and restores Nrf2‐associated antioxidant signaling in bone marrow mesenchymal stem cells, limiting iron ...
Jinwu Bai   +12 more
wiley   +1 more source

Evaluation of sustained blood pressure elevation in children

open access: yesIndian Heart Journal, 2013
Objectives: To document the prevalence and etiology of sustained blood pressure elevation in children. Methods & results: It is a school-based prospective cross-sectional study involving healthy school children in age group of 5–15 years (both sexes ...
Arun Kumar De   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy