Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li+12 more
wiley +1 more source
Predictive value of left ventricular myocardial constructive work in patients with heart failure with preserved ejection fraction and preclinical diastolic dysfunction. [PDF]
Chilingaryan A+3 more
europepmc +1 more source
Diastolic Dysfunction in the Presence of Left Ventricular Systolic Dysfunction: Implications of ß‐Adrenergic Blocking Therapy [PDF]
Michael Kim, Mark R. Starling
openalex +1 more source
Considerations for drug trials in hypertrophic cardiomyopathy
Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant+17 more
wiley +1 more source
Impact of coronary artery calcium on progression of diastolic dysfunction: a cohort study. [PDF]
Choi KH+13 more
europepmc +1 more source
Regional Diastolic Dysfunction in Chronic Chagas' Heart Disease [PDF]
Harry Acquatella
openalex +1 more source
Prognostic role of TAPSE to PASP ratio in outpatients with left ventricular systolic dysfunction
Abstract Aims Few data are available regarding the role of tricuspid annulus plane systolic excursion to pulmonary artery systolic pressure (TAPSE/PASP), a measurement of right ventricular to pulmonary artery coupling, in patients with chronic heart failure and left ventricular systolic dysfunction.
Mauro Riccardi+9 more
wiley +1 more source
Metabolic syndrome, left ventricular diastolic dysfunction and heart failure with preserved ejective fraction. [PDF]
Zhou D+7 more
europepmc +1 more source
Brain Natriuretic Peptide as a Potential Marker of Diastolic Dysfunction in Type 2 Diabetes [PDF]
Nathan Chan, Steven J. Hurel
openalex +1 more source
Sacubitril/valsartan preserves regional cardiac function following myocardial infarction in rats
Parts of the figure were drawn by using pictures from Servier Medical Art. Servier Medical Art by Servier is licensed under a Creative Commons Attribution 3.0 Unported License (https://creativecommons.org/licenses/by/3.0/). Abstract Aims Sacubitril/valsartan (Sac/Val) is used for treatment of heart failure. The effect of Sac/Val on regional dysfunction
Einar Sjaastad Nordén+16 more
wiley +1 more source