Results 131 to 140 of about 1,526,915 (347)

Mitochondria‐endoplasmic reticulum organelle glue as maturation promoter for origination/dimensional dual‐cross cardiomyocytes

BMEMat, EarlyView.
Mitochondria‐endoplasmic reticulum contact sites (MERCS) are areas where the mitochondria and endoplasmic reticulum closely interact. In this study, we utilize synthetic organelle glues to artificially engineer MERCS for regulating cardiomyocyte development, through which the immature and chemo‐plasticity issues of undifferentiated cells are addressed.
Wei Tang, Hao Sun, Chenqi Duan, Jiajia Chang, Yuxing Wang, Ming Zhao, Huiyue Zhao, Shan Lu, Yang Yang, Da Huo   +9 more
wiley   +1 more source

An in-depth analysis of glycosylated haemoglobin level, body mass index and left ventricular diastolic dysfunction in patients with type 2 diabetes

BMC Endocrine Disorders, 2019
Background Glycosylated hemoglobin (HbA1c) has a detrimental impact on the myocardium with left ventricular (LV) diastolic dysfunction. Obesity is a risk factor of type 2 diabetes.
Xin Zuo, Xueting Liu, Runtian Chen, Huiting Ou, Jiabao Lai, Youming Zhang, Dewen Yan   +6 more
doaj   +1 more source

Left ventricular diastolic dysfunction in type 2 diabetes patients: A novel 2D strain analysis based on cardiac magnetic resonance imaging

, 2016
Objective: This study was to develop a strain analysis method to evaluate the left ventricular (LV) functions in type 2 diabetic patients with an asymptomatic LV diastolic dysfunction. \ud \ud Methods: Two groups (10 asymptomatic type 2 diabetic subjects
Chen, Qiang, Li, Zhi-Yong, Gan, Yan
core   +1 more source

Transcatheter Repair of Sinus Venosus Defect Using a 12‐zig Covered Cheatham‐Platinum Stent in Large Superior Vena Cava—Right Atrium Junctions: Early Multicenter Experience

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Sinus venosus defect (SVD) is a rare congenital heart anomaly characterised by an abnormal communication between the atria, often associated with partial anomalous pulmonary venous connection (PAPVC). Traditional surgical repair carries significant risks, prompting exploration into less invasive transcatheter approaches.
Alberto Fuensalida, Eric Rosenthal, Saleha Kabir, Gergely Szantho, Sophia Yong, Demetris Taliotis, Mark Turner, Radwa Bedair   +7 more
wiley   +1 more source

Association between E/e´ ratio and fluid overload in patients with predialysis chronic kidney disease.

PLoS ONE, 2017
BackgroundChronic fluid overload is common in patients with chronic kidney disease (CKD) and can with time lead to diastolic dysfunction and heart failure.
Jae-Seok Kim, Jae-Won Yang, Jin Sae Yoo, Seung Ok Choi, Byoung-Geun Han   +4 more
doaj   +1 more source

Diastolic dysfunction in sickle cell

Blood, 2010
In adults with sickle cell disease (SCD), echocardiographic evidence of diastolic dysfunction is an independent risk factor for death that is additive to pulmonary hypertension. In this issue of Blood, Johnson and colleagues describe echocardiography and polysomnography results from 44 children with SCD.
Gregory J, Kato, Vandana, Sachdev
openaire   +3 more sources

Empagliflozin Improves Left Ventricular Diastolic Dysfunction in a Genetic Model of Type 2 Diabetes

Cardiovascular Drugs and Therapy, 2017
PurposeCardiovascular (CV) diseases in type 2 diabetes (T2DM) represent an enormous burden with high mortality and morbidity. Sodium-glucose cotransporter 2 (SGLT2) inhibitors have recently emerged as a new antidiabetic class that improves glucose ...
N. Hammoudi, Dongtak Jeong, Rajvir Singh, Ahmed Farhat, M. Komajda, E. Mayoux, R. Hajjar, Djamel Lebeche   +7 more
semanticscholar   +1 more source

Unveiling the Microvasculature: The Index of Microcirculatory Resistance and Its Expanding Role in Cardiovascular Care

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Index of microcirculatory resistance (IMR) is a cutting‐edge, wire‐based tool that advances the capability assessment of coronary microvascular function. By utilizing distal coronary pressure and mean transit time under maximal hyperemia, IMR delivers consistent, reproducible insights into the microvasculature's dynamic health.
Joanna Sohn, Matthew A. Soderstrom, Ariana Ramirez, John‐Henry Dean, Raj Shah, Debanshu Roy, Kenneth Stone, Ariel Vinas, Bryan Ramsey, Charles Lin, Robert Chilton   +10 more
wiley   +1 more source

Endurance exercise upregulates mtp expression in aged Drosophila to ameliorate age‐related diastolic dysfunction and extend lifespan

Physiological Reports
Diastolic dysfunction is a major cardiac dysfunction, and an important predisposing factor is age. Although exercise training is often used for the prevention and treatment of cardiovascular disease nowadays, little is currently known about whether ...
Tianhang Peng, Meng Ding, Hanhui Yan, Ping Zhang, Rui Tian, Yin Guo, Lan Zheng   +6 more
doaj   +1 more source

Cardiovascular Magnetic Resonance Deformation Imaging By Feature Tracking For Assessment Of Left And Right Ventricular Structure And Function

, 2014
The copyright of this thesis rests with the author and no quotation from it or information derived from it may be published without the prior written consent of the authorCardiac magnetic resonance (CMR) imaging is the gold standard imaging technique for
Augustine, Daniel
core