Results 121 to 130 of about 1,526,915 (347)

Diastolic dysfunction is more apparent in STZ-induced diabetic female mice, despite less pronounced hyperglycemia

open access: yesScientific Reports, 2018
Diabetic cardiomyopathy is a distinct pathology characterized by early emergence of diastolic dysfunction. Increased cardiovascular risk associated with diabetes is more marked for women, but an understanding of the role of diastolic dysfunction in ...
C. Chandramouli   +12 more
semanticscholar   +1 more source

Striking Bone Marrow Plasmacytosis Resulting From Visceral Leishmaniasis

open access: yes
American Journal of Hematology, EarlyView.
Vishakha Sovani   +2 more
wiley   +1 more source

Integrated Clinical and Proteomic Profiling of CD19 CAR‐T Cell Therapy in Progressive Systemic Sclerosis

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T‐cell therapy in patients with progressive systemic sclerosis. Methods Patients with progressive systemic sclerosis received CD19 CAR‐T cell therapy and were followed longitudinally for safety, clinical efficacy, immune ...
Chenhan Jia   +16 more
wiley   +1 more source

Diastolic Dysfunction in Individuals with Human Immunodeficiency Virus Infection

open access: yesJournal of Cardiac Failure, 2018
Antiretroviral therapy (ART) has been associated with a shift in the epidemiology of HIV-associated cardiomyopathy from a phenotype of primarily left ventricular (LV) systolic dysfunction to LV diastolic dysfunction (DD).
J. Butler   +11 more
semanticscholar   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić   +7 more
wiley   +1 more source

Diastolic dysfunction: from the discovery to the latest updates

open access: yesZaporožskij Medicinskij Žurnal, 2019
Over a long period, chronic heart failure was primarily associated with impaired contractility of the left ventricular myocardium, which is a manifestation of systolic dysfunction. Based on modern ideas about the pathophysiology of CHF syndrome, systolic
T. V. Ashcheulova   +5 more
doaj   +1 more source

Causes of severe diastolic dysfunction.

open access: yes, 2016
Causes of severe diastolic dysfunction.
Shih-Hung Hsiao (3117576)   +1 more
core   +1 more source

The relative contribution of metabolic and structural abnormalities to diastolic dysfunction in obesity

open access: yesInternational Journal of Obesity, 2017
Background:Obesity causes diastolic dysfunction, and is one of the leading causes of heart failure with preserved ejection fraction. Myocardial relaxation is determined by both active metabolic processes such as impaired energetic status and steatosis ...
J. Rayner   +7 more
semanticscholar   +1 more source

Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra   +8 more
wiley   +1 more source

Application of updated guidelines on diastolic dysfunction in patients with severe sepsis and septic shock

open access: yesAnnals of Intensive Care, 2017
Background Left ventricular diastolic dysfunction is suggested to be associated with higher mortality in severe sepsis and septic shock, yet the methods of diagnosis described in the literature are often inconsistent. The recently published 2016 American
David J. Clancy   +5 more
doaj   +1 more source

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