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It has recently become firmly established that patients can experience chronic and acute heart failure with a normal ejection fraction (HFNEF).1–5 We now know this disorder is the dominant form of HF in the community, and that compared with HF with reduced ejection fraction (HFREF), it is increasing in prevalence and incidence,6 causes at least as many
+5 more sources
Introduction and Aim : Diastolic dysfunction is a common finding in end-stage renal disease (ESRD) on regular hemodialysis (HD). Galectin-3 (Gal-3) has emerged as an early biomarker with diagnostic and prognostic values in cardiac dysfunction with ...
Akram Elsadek +4 more
doaj +1 more source
OBJECTIVES The purpose of this study was to investigate the effect of empagliflozin on diastolic function in a nondiabetic heart failure with reduced ejection fraction (HFrEF) scenario and on the pathways causing diastolic dysfunction.
C. Santos-Gallego +11 more
semanticscholar +1 more source
BackgroundLeft ventricular (LV) diastolic dysfunction has been demonstrated to be an independent predictor of the future heart failure. Heart failure is one of the severe complications caused by overt hyperthyroidism.
Huan Li +12 more
doaj +1 more source
Concomitant diastolic dysfunction further interferes with cognitive performance in moderate to severe systolic heart failure. [PDF]
Studies of the relevance of cardiac functional markers to cognitive performance in heart failure (HF) have primarily focused on systolic markers. In this study, we examine whether concomitant diastolic dysfunction further interferes with cognitive ...
Mi-Seung Shin +5 more
doaj +1 more source
Left atrial strain as sensitive marker of left ventricular diastolic dysfunction in heart failure
The purpose of this retrospective analysis was to examine the association of left atrial (LA) strain (i.e. LA reservoir function) with left ventricular diastolic dysfunction (DD) in patients with heart failure with reduced and preserved left ventricular ...
Athanasios Frydas +11 more
semanticscholar +1 more source
Heart failure is a leading cause of hospital admissions in North America. Approximately half of patients with symptoms of heart failure have normal or minimally impaired systolic function and are therefore diagnosed, by exclusion, with diastolic dysfunction. The therapy of diastolic dysfunction to date is largely unsatisfactory.
Maurer, Mathew S. +3 more
openaire +3 more sources
HDAC inhibition improves cardiopulmonary function in a feline model of diastolic dysfunction
Histone deacetylase inhibition counteracts adverse left ventricular remodeling, improves pulmonary function, and reverses diastolic dysfunction. Counteracting cardiopulmonary dysfunction In patients with heart failure, impaired relaxation of the left ...
M. Wallner +23 more
semanticscholar +1 more source
Prevalence and significance of alterations in cardiac structure and function in patients with heart failure and a preserved ejection fraction [PDF]
<p><b>Background:</b> The purpose of this study was to examine the prevalence of abnormalities in cardiac structure and function present in patients with heart failure and a preserved ejection fraction (HFPEF) and to determine whether ...
Michel Komajda +18 more
core +1 more source
Defining left atrial (LA) function has recently emerged as a powerful parameter, particularly in evaluation of left ventricular (LV) diastolic dysfunction (LVDD) and heart failure with preserved ejection fraction.
L. Thomas +4 more
semanticscholar +1 more source

