Results 51 to 60 of about 319,131 (234)

Left ventricular heart failure and pulmonary hypertension [PDF]

, 2015
In patients with left ventricular heart failure (HF), the development of pulmonary hypertension (PH) and right ventricular (RV) dysfunction are frequent and have important impact on disease progression, morbidity, and mortality, and therefore warrant ...
Anton Vonk-Noordegraaf, J. Simon R. Gibbs, Jean-Luc Vachiéry, Kovacs, Lancellotti, Nagueh, Rolf Wachter, Stephan Rosenkranz, Teresa De Marco   +8 more
core   +2 more sources

Pre-Clinical Diastolic Dysfunction

Journal of the American College of Cardiology, 2014
Pre-clinical diastolic dysfunction (PDD) has been broadly defined as left ventricular diastolic dysfunction without the diagnosis of congestive heart failure (HF) and with normal systolic function. PDD is an entity that remains poorly understood, yet has definite clinical significance.
Wan, Siu-Hin, Vogel, Mark W., Chen, Horng H.   +2 more
openaire   +2 more sources

Western Diet-Fed, Aortic-Banded Ossabaw Swine: A Preclinical Model of Cardio-Metabolic Heart Failure. [PDF]

, 2019
The development of new treatments for heart failure lack animal models that encompass the increasingly heterogeneous disease profile of this patient population.
Alex, Linda, Baines, Christopher P, Domeier, Timothy L, Edwards, Jenna C, Emter, Craig A, Ferreira-Nichols, Stephanie C, Ford, David A, Gao, Chen, Ivey, Jan R, Jones, John L, Jurrissen, Thomas J, Klutho, Paula J, Krenz, Maike, McDonald, Kerry S, Olver, T Dylan, Padilla, Jaume, Rau, Christoph, Rector, R Scott, Solaro, R John, Thorne, Pamela K, Veteto, Adam B, Wang, Yibin, Warren, Chad M   +22 more
core  

Echocardiography during submaximal isometric exercise in children with repaired coarctation of the aorta compared with controls [PDF]

, 2019
Objective Patients with repaired coarctation (RCoA) remain at higher risk of cardiac dysfunction, initially often only detected during exercise. In this study, haemodynamics of isometric handgrip (HG) and bicycle ergometry (BE) were compared in patients ...
Bové, Thierry, Coomans, Ilse, De Wolf, Daniël, Dequeker, Laure, Panzer, Joseph, Rietzschel, Ernst, Vandekerckhove, Kristof   +6 more
core   +1 more source

Adiponectin Deficiency, Diastolic Dysfunction, and Diastolic Heart Failure [PDF]

Endocrinology, 2010
Abstract Aldosterone infusion results in left ventricular hypertrophy (LVH) and hypertension and may involve profibrotic and proinflammatory mechanisms. In turn, hypertension is the major cause of diastolic heart failure (HF). Adiponectin, an adipose-derived plasma protein, exerts antiinflammatory and anti-hypertrophic effects and is ...
Flora, Sam, Toni-Ann S, Duhaney, Kaori, Sato, Richard M, Wilson, Koji, Ohashi, Saki, Sono-Romanelli, Akiko, Higuchi, Deepa S, De Silva, Fuzhong, Qin, Kenneth, Walsh, Noriyuki, Ouchi   +10 more
openaire   +2 more sources

Left Ventricle Diastolic Function in Patients Underwent Chemotherapy with Doxorubicin

Majalah Kardiologi Indonesia, 2013
Background. Doxorubicin is one of the first-line chemoterapy against many form of neoplasm but the use is hampered by its cardiotoxic poten-tial with the end result of congestive heart failure.
Januar Wibawa Martha, Sunarya Surianata, Amiliana M Soesanto   +2 more
doaj   +1 more source

Left Ventricular Diastolic Dysfunction in Asymptomatic Type 2 Diabetes Mellitus [PDF]

Kirkuk Journal of Medical Sciences
Background: Type 2 diabetes mellitus is a global public health issue. Left ventricular diastolic dysfunction is the earliest diabetic cardiovascular complication.
Marwa Suleman, Mohammed khalaf
doaj   +1 more source

Therapeutic Effect of Targeting Branched-Chain Amino Acid Catabolic Flux in Pressure-Overload Induced Heart Failure. [PDF]

, 2019
Background Branched-chain amino acid (BCAA) catabolic defect is an emerging metabolic hallmark in failing hearts in human and animal models. The therapeutic impact of targeting BCAA catabolic flux under pathological conditions remains understudied ...
Chen, Mengping, Chuang, David T, Gao, Chen, Ren, Shuxun, Sun, Haipeng, Wang, Menglong, Wang, Yibin, Wynn, R Max, Yu, Jiayu   +8 more
core   +1 more source

Decreased soluble guanylate cyclase contributes to cardiac dysfunction induced by chronic doxorubicin treatment in mice [PDF]

, 2017
Aims: The use of doxorubicin, a potent chemotherapeutic agent, is limited by cardiotoxicity. We tested the hypothesis that decreased soluble guanylate cyclase (sGC) enzyme activity contributes to the development of doxorubicin-induced cardiotoxicity ...
Allen, Kaitlin, Bartunek, Jozef, Beerens, Manu, Bloch, Donald B, Bloch, Kenneth D, Brouckaert, Peter, Buys, Emmanuel S, Caluwe, Ellen, Gillijns, Hilde, Janssens, Stefan P, Nathan, Daniel I, Scherrer-Crosbie, Marielle, Swinnen, Melissa, Tainsh, Robert E, Vandenwijngaert, Sara, Walravens, Ann-Sophie   +15 more
core   +1 more source

Looking for Diastolic Dysfunction [PDF]

Circulation, 2002
To the Editor: Zile et al1 simplify the diagnosis of diastolic dysfunction by offering an easy approach: normal ejection fraction in a patient with heart failure strongly suggests diastolic dysfunction. Still, one needs an echocardiogram. I am surprised that they, like others,2,3⇓ do not make this difficult-seeming diagnosis even easier: if a patient ...
openaire   +2 more sources