Results 141 to 150 of about 924,787 (374)

Decursin‐Loaded Nanovesicles Target Macrophages Driven by the Pathological Process of Atherosclerosis

Advanced Science, EarlyView.
This study presents decursin, a traditional Chinese medicine monomer, that inhibits lipid accumulation and inflammation in atherosclerosis through PKCδ interaction. A novel targeted delivery system (ALD@EM) is developed to overcome decursin's short half‐life, combining antibody‐mediated targeting, LDL‐facilitated chemotaxis, and enhanced macrophage ...
Hui Chen, Yifeng Zhang, Mirenuer Aikebaier, Yawei Du, Yan Liu, Qing Zha, Lan Zheng, Shuyao Shan, Yanping Wang, Jiawei Chen, Yiping Li, Ke Yang, Ying Yang, Wenguo Cui   +13 more
wiley   +1 more source

Leucine‐Rich Repeat‐Containing G Protein‐Coupled Receptor 6 Ameliorates Pressure Overload‐Induced Cardiac Hypertrophy by Regulating Cardiomyocyte Metabolic Reprogramming

Advanced Science, EarlyView.
LGR6 overexpression ameliorates cardiac hypertrophy by regulating metabolic reprogramming through USP4‐PPARα pathway. Abstract Metabolic reprogramming is a pivotal mechanism in the pathogenesis of pathological cardiac hypertrophy. Leucine‐rich repeat‐containing G protein‐coupled receptor 6 (Lgr6) has emerged as a significant player in cardiovascular ...
Mengmeng Zhao, Jianfang Liu, Shanshan Peng, Zihui Zheng, Siqi Liu, Jun Wan, Yao Xu, Menglong Wang   +7 more
wiley   +1 more source

The study of left ventricular diastolic function by Doppler echocardiography: the essential for the clinician

Heart International, 2007
An abnormal diastolic function of left ventricle represents the main pathophysiological mechanism responsible for different clinical states such as restrictive cardiomyopathy, infiltrative myocardial disease and, specially, diastolic heart failure (also ...
Livio Dei Cas, Francesco Fracassi, Emanuela Pulcini, Diego Maffeo, Pompilio Faggiano, Enrico Vizzardi, Savina Nodari   +6 more
doaj   +1 more source

Wearable Hyperspectral Photoplethysmography Allows Continuous Monitoring of Exercise‐Induced Hypertension

Advanced Science, EarlyView.
A wearable hyperspectral photoplethysmography (HS‐PPG) is reported for continuous blood pressure (BP) monitoring. The HS‐PPG module integrates an ultrathin double‐folded solid immersion grating microspectrometer (DFSIG‐µSPEC), achieving a high spectral resolution of 3.4 nm.
Jung‐Woo Park, Jaehyeok Park, Jaehun Jeon, Seongok Chae, Gi Beom Kim, Geonhui Han, Hyung‐Soon Park, Yong Jeong, Ki‐Hun Jeong   +8 more
wiley   +1 more source

Sex differences in left ventricular afterload and diastolic function are independent from the aortic size. [PDF]

, 2019
学位記番号 ...
Sorimachi, Hidemi, ソリマチ, ヒデミ, 反町, 秀美   +2 more
core  

Left ventricular systolic and diastolic function in coronary artery disease: effects of revascularization on exercise-induced ischemia. [PDF]

, 1985
John D. Carroll, Otto M. Hess, H O Hirzel, Marko Turina, H P Krayenbuehl   +4 more
openalex   +1 more source

Flavonifractor Plautii or Its Metabolite Desaminotyrosine as Prophylactic Agents for Alleviating Myocardial Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
The gut microbiome is a potential target for treating cardiovascular disease. It is found that prophylactic administration of Flavonifractor plautii or its metabolite desaminotyrosine (DAT) exerts pleiotropic cardioprotective effects via promoting cardiomyocyte survival and attenuating cardiac inflammation against myocardial ischemia/reperfusion (I/R ...
Heng Du, Xu Liu, Jianghua Shen, Hailong Yuan, Hao Zhang, Gan Xi, Yujing Li, Yuhan Wang, Jiahe Zhang, Chaofan Yang, Pengfei Xu, Jiawan Wang, Fang Wang, Siqi Liu, Yanan Zhou, Qi Gu, Jingjing Lu, Tuo Wei, Zeyu Gao, Jingyi Zang, Jun Wang, Moshi Song   +21 more
wiley   +1 more source

An Improved Approach for Cardiac MRI Segmentation based on 3D UNet Combined with Papillary Muscle Exclusion [PDF]

arXiv
Left ventricular ejection fraction (LVEF) is the most important clinical parameter of cardiovascular function. The accuracy in estimating this parameter is highly dependent upon the precise segmentation of the left ventricle (LV) structure at the end diastole and systole phases.
arxiv  

Doppler echocardiographic assessment of left ventricular systolic and diastolic function in mild hypertension. [PDF]

, 1987
Julius M. Gardin, J. I. M. Drayer, Michael A. Weber, Mary K. Rohan, Margaret Knoll, Vincent W.C. Shu, Raymond Garcia, D. D. Brewer, Walter L. Henry   +8 more
openalex   +1 more source

Fish Swim Bladder‐Derived ECM Hydrogels Effectively Treat Myocardial Ischemic Injury through Immunomodulation and Angiogenesis

Advanced Science, EarlyView.
A unique hydrogel based on extracellular matrix from fish swim bladder, which is suitable for transcatheter delivery and possesses remarkable reparative capabilities for treating heart failure, is developed. It emerges as a multi‐effect factor profoundly influencing inflammation regulation, angiogenesis, and myocardial metabolism.
Yulong Fu, Canran Gao, Hailing Zhang, Jing Liu, Boxuan Li, Wei Chen, Xiuping Chen, Xue Lin, Ligang Fang, Zhihong Wang   +9 more
wiley   +1 more source