Results 61 to 70 of about 11,141,403 (375)

Interval training normalizes cCardiomyocyte function, diastolic Ca²⁺ control, and SR Ca²⁺ release synchronicity in a mouse model of diabetic cardiomyopathy [PDF]

, 2009
In the present study we explored the mechanisms behind excitation-contraction (EC)-coupling defects in cardiomyocytes from mice with type-2 diabetes (db/db), and determined whether 13-weeks of aerobic interval training could restore cardiomyocyte Ca2 ...
Aasum, E., Catalucci, D., Ceci, M., Condorelli, G., Høydal, M.A., Kemi, O.J., Larsen, T., Rolim, N., Smith, G.L., Stølen, T.O., Wisløff, U.   +10 more
core   +2 more sources

Anthracyclines induce early changes in left ventricular systolic and diastolic function: A single centre study

PLoS ONE, 2017
Aims 2 dimensional (2D) strain analysis detects subclinical left ventricular (LV) systolic dysfunction. Our aim was to evaluate changes in LV systolic and diastolic function in breast cancer patients early after anthracycline chemotherapy, and to ...
Anita Boyd, P. Stoodley, D. Richards, R. Hui, P. Harnett, K. Vo, T. Marwick, L. Thomas   +7 more
semanticscholar   +1 more source

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura, Kentaro Ueno, Takuro Nishikawa, Yoshihiro Takahashi, Koji Nakae, Yasuhiro Okamoto   +5 more
wiley   +1 more source

Empagliflozin directly improves diastolic function in human heart failure

European Journal of Heart Failure, 2018
Empagliflozin, a clinically used oral antidiabetic drug that inhibits the sodium‐dependent glucose co‐transporter 2, has recently been evaluated for its cardiovascular safety.
S. Pabel, S. Wagner, H. Bollenberg, P. Bengel, Á. Kov́acs, C. Schach, P. Tirilomis, J. Mustroph, A. Renner, J. Gummert, T. Fischer, S. Van Linthout, C. Tschöpe, K. Streckfuss-Bömeke, G. Hasenfuss, L. Maier, N. Hamdani, S. Sossalla   +17 more
semanticscholar   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Assessment of myocardial diastolic function in adolescents with essential hypertension

Zdorovʹe Rebenka
Background. Left ventricular diastolic dysfunction is a clinically significant impairment characterized by a reduced ability of the myocardium to fill adequately during the diastolic phase.
В.В. Ніконова, В.В. Ніконов   +1 more
doaj   +1 more source

Correlation Between 25-Hydroxyvitamin D Level and Cardiac Diastolic Dysfunction in Chinese Adults with Early-Onset Type 2 Diabetes Mellitus: A Cross-Sectional Study

Diabetes, Metabolic Syndrome and Obesity, 2021
Lei Xiu, Xiao-ai Yao, Tao Jiang Department of Endocrinology, Beijing Shijitan Hospital, Capital Medical University, Beijing, 100038, People’s Republic of ChinaCorrespondence: Tao JiangDepartment of Endocrinology, Beijing Shijitan Hospital, Capital ...
Xiu L, Yao X, Jiang T
doaj  

Do patients with suspected heart failure and preserved left ventricular systolic function suffer from "diastolic heart failure" or from misdiagnosis? A prospective descriptive study [PDF]

, 2000
OBJECTIVES: To characterise the clinical features of patients with suspected heart failure but preserved left ventricular systolic function to determine if they have other potential causes for their symptoms rather than being diagnosed with 'diastolic ...
Caruana, L., Davie, A.P., McMurray, J., Petrie, M.C.   +3 more
core   +2 more sources

Basilar Artery Occlusion Stroke Managed With Tenecteplase Versus Alteplase Before Endovascular Treatment (BAO‐TNK)

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To compare the effectiveness and safety of tenecteplase (TNK) versus alteplase (TPA) in patients with basilar artery occlusion prior to endovascular treatment (EVT). Methods In this retrospective multicenter study (BAO‐TNK), we analyzed consecutive BAO patients from 14 U.S.
Rahul R. Karamchandani, Dylan N. Wolman, Tyler M. Bielinski, Nitin Goyal, Jeremy B. Rhoten, Mahesh V. Jayaraman, Christian T. Sidebottom, Bradley A. Gross, Alhamza R. Al‐Bayati, Mohamed F. Doheim, Matthew K. Tobin, Anoop Chinthala, Avi Gajjar, Justin Mascitelli, Matthew R. Webb, Jan‐Karl Burkhardt, Kyle W. Scott, Visish Srinivasan, Daniel Tonetti, Manisha Koneru, David J. Altschul, Dhrumhil Vaishnav, Sumeet Multani, Thana Theofanis, William J. Ares, Je Yeong Sone, Ramin Zand, Sasan Bahrami, Jiang Li, Gary Defilipp, Dale Strong, Radmehr Torabi, Krisztina Moldovan, Kelsey E. Kline, Clemens M. Schirmer, Raul G. Nogueira, Alexandra R. Paul, Bradley N. Bohnstedt, Philipp Hendrix   +38 more
wiley   +1 more source

Diastolic Dysfunction With Preserved Ejection Fraction After the Fontan Procedure

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Heart failure phenotyping in single‐ventricle Fontan patients is challenging, particularly in patients with normal ejection fraction (EF). The objective of this study was to identify Fontan patients with abnormal diastolic function, who are ...
Shahryar M. Chowdhury, Eric M. Graham, Carolyn L. Taylor, Andrew Savage, Kimberly E. McHugh, Stephanie Gaydos, Arni C. Nutting, Michael R. Zile, Andrew M. Atz   +8 more
doaj   +1 more source