Is diazepam an antidepressant? [PDF]
British Journal of Psychiatry, 1989 In double-blind sequential study, diazepam was compared with the proven antidepressant moclobemide, in patients with atypical depression. Both agents significantly improved depression ratings over eight weeks of treatment. Diazepam was a significantly better antidepressant than moclobemide at four weeks, although not at eight weeks. All patients ceased
Brian Davies +3 more
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Diazepam in cardioversion [PDF]
Canadian Anaesthetists’ Society Journal, 1971 Ce travail decrit nos experiences au cours de 161 cardioversions par courant direct, dont 76 ont ete pratiquees sous anesthesie au diazepam seul et 85 sous anesthesie par divers agents. Generalement le premier choc etait de 100 watts seconde, et les suivants, si besoin, allaient en s’accroissant a partir de 100 watts seconde. Dans le groupe du diazepam,
Jose F. Lopez +2 more
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Diazepam, alcohol use and violence among male young offenders: 'the devil's mixture’ [PDF]
, 2011 Citation for published version (APA): Forsyth, A., Khan, F., & McKinlay, W. (2011). Diazepam, alcohol use and violence among male young offenders: 'the devil's mixture’. Drugs: Education, Prevention and Policy, 18(6), 468-476.
Alasdair J. M. Forsyth +5 more
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Tetramethylenedisulfotetramine alters Ca²⁺ dynamics in cultured hippocampal neurons: mitigation by NMDA receptor blockade and GABA(A) receptor-positive modulation. [PDF]
, 2012 Tetramethylenedisulfotetramine (TETS) is a potent convulsant that is considered a chemical threat agent. We characterized TETS as an activator of spontaneous Ca²⁺ oscillations and electrical burst discharges in mouse hippocampal neuronal cultures at 13 ...
Cao, Zhengyu +5 more
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Behavioral Comorbidities and Drug Treatments in a Zebrafish scn1lab Model of Dravet Syndrome. [PDF]
, 2017 Loss-of-function mutations in SCN1A cause Dravet syndrome (DS), a catastrophic childhood epilepsy in which patients experience comorbid behavioral conditions, including movement disorders, sleep abnormalities, anxiety, and intellectual disability.
Baraban, Scott C +2 more
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Treatments for spasticity and pain in multiple sclerosis: a systematic review [PDF]
, 2003 Objectives: To identify the drug treatments currently available for the management of spasticity and pain in multiple sclerosis (MS), and to evaluate their clinical and cost-effectiveness.
Beard, S.M., Hunn, A., Wight, J.
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Clinical considerations in transitioning patients with epilepsy from clonazepam to clobazam: a case series. [PDF]
, 2014 IntroductionIn treating refractory epilepsy, many clinicians are interested in methods used to transition patients receiving clonazepam to clobazam to maintain or increase seizure control, improve tolerability of patients' overall drug therapy regimens ...
Chung, Steve +4 more
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A detailed analysis of online pharmacy characteristics to inform safe usage by patients [PDF]
, 2015 Background: Evidence suggests that consumers potentially put themselves at risk when purchasing medicines on-line. Whilst logos provided by regulators may provide some level of reassurance there may be other indicators which could be used by consumers to
AB Jena +8 more
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Experimental versus theoretical log D7.4, pKa and plasma protein binding values for benzodiazepines appearing as new psychoactive substances [PDF]
, 2018 The misuse of benzodiazepines as new psychoactive substances is an increasing problem around the world. Basic physicochemical and pharmacokinetic data is required on these substances in order to interpret and predict their effects upon humans ...
Manchester, Kieran R. +2 more
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Titanocene anticancer complexes and their binding mode of action to human serum albumin: a computational study [PDF]
, 2011 Due to the pivotal role played by human serum albumin (HSA) in the transport and cytotoxicity of titanocene complexes, a docking study has been performed on a selected set of titanocene complexes to aid in the current understanding of the potential mode ...
Nutt, David R. +3 more
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