A Short Review on the Intranasal Delivery of Diazepam for Treating Acute Repetitive Seizures
Pharmaceutics, 2020 Benzodiazepines such as diazepam, lorazepam and midazolam remained the mainstay of treatment for acute repetitive seizures (ARS). The immediate care for ARS should often begin at home by a caregiver.
Sai H. S. Boddu, Sneha Kumari
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Diazepam exposure associated with an increased risk of acute kidney injury in children: an observational cohort study [PDF]
BMC PediatricsBackground Potentially nephrotoxic drugs play an important role in acute kidney injury (AKI) in children. In the previous pharmacovigilance study, we found a statistical correlation between diazepam and AKI in children, but the causality needs to be ...
Miao Zhang +6 more
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Epilepsia, 2021 A Phase 3 open‐label safety study (NCT02721069) evaluated long‐term safety of diazepam nasal spray (Valtoco) in patients with epilepsy and frequent seizure clusters.
J. Wheless +14 more
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Epilepsia, 2021 Seizure clusters must be treated quickly and effectively to prevent progression to prolonged seizures and status epilepticus. Rescue therapy for seizure clusters has focused on the use of benzodiazepines.
J. Cloyd +3 more
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Influence of Internal Structure of the Sorbents on Diazepam Sorption from Simulated Intestinal Fluid
Applied Sciences, 2021 The capacity of natural Na-montmorillonite and activated charcoal for sorption of diazepam from simulated intestinal fluid (SIF) was studied. The main characteristics of the sorbents were determined.
Mircea Stefan +4 more
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Effect of diazepam on some physiological and productive traits of Cobb hybrid broiler chickens [PDF]
Iraqi Journal of Veterinary Sciences, 2008 The study was carried out to investigate the effect of diazepam in drinking water on some productive and physiological traits of hybrid (Cobb500) broiler chickens.
H. M. Hameed, S. H. Tohala
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Neurology International, 2021 Valtoco® is a new FDA-approved nasal spray version of diazepam indicated for the treatment of acute, intermittent, and stereotypic episodes of frequent seizure activity in epilepsy patients six years of age and older.
Elyse M. Cornett +8 more
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Pharmacodynamic and pharmacokinetic effects of flumazenil and theophylline application in rats acutely intoxicated by diazepam [PDF]
Vojnosanitetski Pregled, 2009 Background/Aim. The majority of symptoms and signs of acute diazepam poisoning are the consequence of its sedative effect on the CNS affecting selectively polisynaptic routes by stimulating inhibitory action of GABA.
Šegrt Zoran +7 more
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A bibliometric analysis of the recent advances in diazepam from 2012 to 2021
Frontiers in Pharmacology, 2022 Background: Diazepam is a classic benzodiazepine drug that has been widely used for disorders such as anxiety, sleep disorders, and epilepsy, over the past 59 years. The study of diazepam has always been an important research topic.
Ming Zhang +7 more
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Determination of diazepam and its metabolites in serum by the use of liquid chromatography: Mass spectrometry method [PDF]
Vojnosanitetski Pregled, 2007 Background/Aim. Diazepam is a benzodiazepine anxyolitic. Metabolism of diazepam takes place in liver which generates pharmacologically active metabolites N-desmethyldiazepam, temazepam and oxazepam.
Đorđević Snežana, Kilibarda Vesna
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