Results 301 to 310 of about 109,445 (330)
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Acta Medica Scandinavica, 1975
Abstract Diazepam has been used to an increasing extent in cardioversion, since avoiding general anaesthesia simplifies the procedure. The present study concerns the effect of diazepam on BP and blood gases in 13 cases of cardioversion. A moderate fall of both systolic and diastolic BP occurred. The arterial pO2 and pCO2 did not change significantly.
O. Nyquist +3 more
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Abstract Diazepam has been used to an increasing extent in cardioversion, since avoiding general anaesthesia simplifies the procedure. The present study concerns the effect of diazepam on BP and blood gases in 13 cases of cardioversion. A moderate fall of both systolic and diastolic BP occurred. The arterial pO2 and pCO2 did not change significantly.
O. Nyquist +3 more
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New England Journal of Medicine, 1965
THE conversion of cardiac arrhythmias by directcurrent countershock has become widely accepted but has usually required the use of general anesthesia, with its attendant hazards and practical problems. The last 15 patients undergoing cardioversion in our laboratory have been prepared for electric shock with a single intravenous injection of diazepam ...
D. O. Nutter, R. A. Massumi
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THE conversion of cardiac arrhythmias by directcurrent countershock has become widely accepted but has usually required the use of general anesthesia, with its attendant hazards and practical problems. The last 15 patients undergoing cardioversion in our laboratory have been prepared for electric shock with a single intravenous injection of diazepam ...
D. O. Nutter, R. A. Massumi
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CARDIOPULMONARY EFFECTS OF DIAZEPAM
Survey of Anesthesiology, 1973Eighteen patients with appreciable obstructive lung disease and 18 patients without measurable mechanical lung impairment were given intravenous diazepam to permit endoscopy. Doses of diazepam required for comparable level of anesthesia were used. There was an increase in the heart rate, and there were decreases in the blood pressure, stroke volume ...
K. Prasad +4 more
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Allergy, 2002
A 28-year-old nurse experienced collapse and generalized urticaria while she was undergoing a gastroscopy for suspected Helicobacter pylori infection. Before the start of the procedure, lidocaine (lignocaine) oral spray and 10 mg intravenous diazepam was administered; in addition, 1 mg flumazenil was given intravenously at the end of gastroscopy.
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A 28-year-old nurse experienced collapse and generalized urticaria while she was undergoing a gastroscopy for suspected Helicobacter pylori infection. Before the start of the procedure, lidocaine (lignocaine) oral spray and 10 mg intravenous diazepam was administered; in addition, 1 mg flumazenil was given intravenously at the end of gastroscopy.
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Metabolism of diazepam in rabbits
Archives of Biochemistry and Biophysics, 1964Abstract Urines of rabbits treated with large doses of diazepam were analyzed. After hydrolysis three compounds were isolated and identified: 2-methylamino-5-chlorobenzophenone (III), 2-amino-5-chlorobenzophenone (IV), and 2-methylamino-5-chloro-4′-hydroxybenzophenone (V).
G. Jommi, P. Manitto, M.A. Silanos
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Potencies of diazepam metabolites in rats trained to discriminate diazepam
Life Sciences, 1986The dose-response relationships of diazepam and several of its metabolites were determined in rats trained to discriminate diazepam (3 mg/kg) from saline in a two-lever operant choice task. Generalization of the diazepam stimulus was found to occur with temazepam and oxazepam, which were nearly equipotent with diazepam, and also with desmethyldiazepam,
David A. Brase +3 more
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Cardiovascular changes in dogs given diazepam and diazepam-ketamine
American Journal of Veterinary Research, 1986SUMMARY The cardiopulmonary consequences of diazepam (0.5 mg/kg, iv) followed by ketamine (10 mg/kg, iv) were evaluated in 11 dogs. Diazepam did not exhibit a tranquilizing effect and was frequently associated with excessive excitement. It produced minimal cardiopulmonary effects, except for a significant increase in heart rate. Ketamine administration
S C, Haskins, T B, Farver, J D, Patz
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Clobazam and diazepam in anxiety
Journal of Clinical Psychopharmacology, 1981The anxiolytic effects of clobazam, diazepam, and placebo were compared in a 4-wk double-blind study of 159 anxious outpatients, primarily from family practice. Clobazam (30 to 80 mg/day) and diazepam (15 to 40 mg/day) were found to induce similar side effect, primarily sedation, and although both active drugs induced greater clinical improvement than ...
Robert Weinstock +9 more
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Clinical Pharmacokinetics of Diazepam
Clinical Pharmacokinetics, 1978Diazepam is still one of the most used of the benzodiazepine group of drugs. Extensive studies over 10 years have defined a fairly complete profile of its kinetics. Minor aspects relating to patterns of its metabolism and excretion in certain age groups and in some disease states remain to be described quantitatively.
M. Mandelli +2 more
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