Preparation and Reactions of 1, 5-bis (p-substituted Phenyl) Octahydro-3, 7-Disubstituted-1, 5-Diazocines [PDF]
, 1976 The purpose of this research was to synthesize and study the reactions of 1,5-bis-(p-substituted phenyl)octahydro-3, 7-disubstituted-1, 5-diazocines.
Odle, Roy R.
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Spatiotemporal control in biomedicine: photoswitchable peptides and foldamers
British Journal of Pharmacology, Volume 182, Issue 19, Page 4458-4465, October 2025.Photopharmacology integrates light‐based technology with pharmacology to achieve precise control over biological processes, offering non‐invasive activation and spatiotemporal regulation of biomolecular activity. Within this field, photoswitchable peptides and foldamers provide a powerful approach in precision medicine, enabling reversible ...
Eszter Erdei +5 more
wiley +1 more source
Synthetic studies toward A-74528 and synthesis of cyclic azobenzenes [PDF]
, 2020 Part I: Synthetic studies toward A-74528 With thirty carbons A-74528 is one of the two largest type II polyketides known to date. It has a promising bioactivity linked to modulating RNAse L activity and mRNA degradation as part of the innate immune ...
Maier, Martin
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Erweiterung des Repertoires an lichtschaltbaren unnatürlichen Aminosäuren für das Enzym‐Engineering
Angewandte Chemie, Volume 137, Issue 38, September 15, 2025.Enzym‐Engineering mit lichtschaltbaren unnatürlichen Aminosäuren (lsUAs) birgt ein hohes Potenzial für Anwendungen wie die Biokatalyse. Wir erweitern hier das aktuell vorhandene Repertoire mit lsUAs, welche vielseitigere Eigenschaften aufweisen, um den Weg für eine fortschrittlichere Etablierung der Lichtkontrolle in Enzymen zu ebnen. Wir berichten die
Caroline Hiefinger +11 more
wiley +1 more source
Expanding the Repertoire of Photoswitchable Unnatural Amino Acids for Enzyme Engineering
Angewandte Chemie International Edition, Volume 64, Issue 38, September 15, 2025.Enzyme engineering with photoswitchable unnatural amino acids (psUAAs) has a high potential for applications such as biocatalysis. Here, we extend the current repertoire of psUAAs to include more versatile properties paving the way to more advanced photocontrol engineering.
Caroline Hiefinger +11 more
wiley +1 more source
SYNTHESIS OF CYCLIC AZOBENZENE ANALOGUES FOR INCORPORATION INTO OLIGONUCLEOTIDES, PEPTIDES AND POLYMERS [PDF]
, 2014 (A) In recent years, considerable amount of effort has contributed towards enhancing our understanding of the new photoswitch, cyclic azobenzene, particularly from the theoretical point of view.
Joshi, Dhruval Kumar
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A Platform for the Development of Highly Red‐Shifted Azobenzene‐Based Optical Tools
Angewandte Chemie, Volume 137, Issue 32, August 4, 2025.Our platform is built on a combination of chemical synthesis, NMR, UV–vis, and quantum chemical studies. The dfdc azobenzene scaffold provides efficient photoswitching with red light and the ability to fine‐tune relaxation times. A TD‐DFT‐based workflow allows the in silico design of photoswitches with properties tailored to desired applications.
Kyra Lützel +17 more
wiley +1 more source
(A) Photoregulation of DNA Functions by Cyclic Azobenzene-tethered Oligonucleotides (B) Site-specific Fluorescent Labeling of DNA using Inverse Electron Demand Diels-Alder Reaction between trans-Cyclooctene Derivatives and BODIPY-Tetrazine Adducts [PDF]
, 2015 (A) Most azobenzene-based photoswitches require UV light for photoisomerization, which limit their applications in biological systems due to possible photodamage.
Eljabu, Fatma Mohamed
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Experimental and Theoretical Investigations in Solid Phase
Reaction Kinetics and Noncovalent Interactions in Water [PDF]
, 2007 Factors affecting reaction rates in polystyrene beads used in solid phase organic synthesis have been studied. The role of diffusion and reagent partitioning has been examined theoretically and experimentally.
Bhayana, Brijesh
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Conjugated Nanobelts Based on N-Hetero[(6.)m8]ncyclacene [PDF]
This study introduces a novel design of N-doped conjugated nanobelts, derived from a specific structural unit found in carbon schwarzites, a type of negatively curved carbon allotrope.
Aratani, Naoki +5 more
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