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Molecular recognition and sensing of dicarboxylates and dicarboxylic acids

Organic & Biomolecular Chemistry, 2020
This review outlines challenges faced in recognition and detection of dicarboxylic acids and dicarboxylates and strategies used to obtain effective and observable interactions in the period from 2014 to 2020.
Stephen M. Butler, Katrina A. Jolliffe
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Xenobiotic Conjugation with Dicarboxylic Acids

Current Drug Metabolism, 2018
Although it is believed widely that the various routes of xenobiotic metabolism are now all known and effectively understood, occasionally there emerges a metabolite that signals a novel biotransformation pathway, especially where the xenobiotic may in some way interact with the myriad processes of intermediary metabolism.
Stephen C, Mitchell, Glyn B, Steventon
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Biphenyl-2,2'-dicarboxylic acid (diphenic acid)

Acta Crystallographica Section C Crystal Structure Communications, 1987
C 14 H 10 O 4 cristallise dans le systeme monoclinique avec le groupe d'espace P2 1 /c. Affinement de la structure jusqu'a 0,064. La maille unitaire contient 2 molecules independantes.
F. R. Fronczek   +3 more
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Dicarboxylic acid

Dicarboxylic acids are organic compounds that contain two functional carboxylic acid (–COOH) groups. Industrially, they are important in producing polyester, polyols, polyamides, and nylon and as a precursor to active pharmaceutical ingredients and additives. Dicarboxylic acids are important water-soluble components of atmospheric aerosols. Succinic,
Patel, Shuchi, Parmar, Mayur S
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Long-chain dicarboxylic acids

Journal of Colloid and Interface Science, 1977
Abstract Aqueous dispersions of heavy-metal salts of 5-(and 6-)carboxy-4-hexyl-2-cyclohexen-1-yl octanoic acids, denoted by H2D, were prepared by direct mixing of solutions of the metal nitrates with solutions of Na2D. With any particular concentration of D2− ion, it was found that the turbidity increased sharply when the concentration of a metal ion
Junryo Mino, Egon Matijević
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DIPHENYLMETHANB-3,3′-DICARBOXYLIC ACID

Canadian Journal of Chemistry, 1964
The major condensation product of benzoic acid with formaldehyde in the presence of sulphuric acid was shown to be diphenylmethane-3,3′-dicarboxylic acid.
R. W. Beattie, R. H. F. Manske
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Dicarboxylic Acid

2014
Dicarboxylic acids are organic compounds that contain two functional carboxylic acid (–COOH) groups. Industrially, they are important in production of polyester, polyols, polyamides, and nylon and as a precursor to active pharmaceutical ingredients and additives.
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Rat liver metabolism of dicarboxylic acids

American Journal of Physiology-Gastrointestinal and Liver Physiology, 1989
Recently, we demonstrated in rat liver that dicarboxylic acids containing more than five carbons can be activated by a microsomal dicarboxylyl-CoA synthetase (J. Vamecq, E. de Hoffmann, and F. Van Hoof. Biochem. J. 230: 683-693, 1985). The products of this reaction, dicarboxylyl-CoA esters, were found to be substrates for an H2O2-generating ...
J, Vamecq, J P, Draye, J, Brison
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Dicarboxylic Acid Dipeptide Neutral Endopeptidase Inhibitors

Journal of Medicinal Chemistry, 1995
The synthesis of three series of dicarboxylic acid dipeptide neutral endopeptidase 24.11 (NEP) inhibitors is described. In particular, the amino butyramide 21a exhibited potent NEP inhibitory activity (IC50 = 5.0 nM) in vitro and in vivo. Blood levels of 21a were determined using an ex vivo method by measuring plasma inhibitory activity in conscious ...
G M, Ksander   +7 more
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5,8-Dimethoxynaphthalene-1,6-dicarboxylic Acid

Acta Crystallographica Section C Crystal Structure Communications, 1997
The title compound, C14H12O6, crystallized in the centrosymmetric space group Pbca but does not exhibit hydrogen bonding of the usual cyclic dimer type about a center of symmetry or otherwise. Each molecule is linked to six neighbors by eight hydrogen bonds, which leads, in this structure, to a rich pattern of chains.
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