Results 121 to 130 of about 1,558,397 (364)
Single-molecule analysis of processive double-stranded RNA cleavage by Drosophila Dicer-2 [PDF]
, 2021 Masahiro Naganuma +2 more
openalex +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
The Challenges of Infrastructure Privatisation [PDF]
Privatisierung, Infrastruktur, Deregulierung, Politische Reform, Privatization, Public infrastructure, Deregulation, Political ...
Ioannis N. Kessides
core
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
The Provision of Water Services in the UK [PDF]
Wasserversorgung, Privatisierung, Regulierung, Großbritannien, Water supply, Privatization, Regulation, United ...
Thomas Zabel
core
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Health Insurance Reform in the Netherlands [PDF]
Krankenversicherung, Reform, Gesundheitsreform, Niederlande, Health insurance, Reform, Health care reform ...
Jürgen Wasem +2 more
core
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Privatisation and Regulation of Water Supply - Overview [PDF]
Wasserversorgung, Privatisierung, Regulierung, Water supply, Privatization ...
Johann Wackerbauer
core
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source