Results 191 to 200 of about 1,558,397 (364)

Human DICER helicase domain recruits PKR and modulates its antiviral activity

, 2021
Thomas Montavon, Morgane Baldaccini, Mathieu Lefèvre, Erika Girardi, Béatrice Chane-Woon-Ming, Mélanie Messmer, Philippe Hammann, Johana Chicher, Sébastien Pfeffer   +8 more
openalex   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Comparing Interactive Machine Learning and Unassisted Segmentation of Geographic Atrophy From Fundus Autofluorescence. [PDF]

Transl Vis Sci Technol
Bearce B, McNamara S, Kinder S, Manoharan N, Lisker A, Arguinchona L, Marks B, Roseto I, Barrientos L, Milner D, Gnanaraj R, Gill Z, Tukel M, Abe-Ridgway K, Mandava N, Singh P, Nebbia G, Kalpathy-Cramer J.   +17 more
europepmc   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Index

América Latina Hoy, 2018
Secretaría de Redacción ALH
doaj   +1 more source

Comparative Analysis of Deep Learning Architectures for Automatic Tooth Segmentation in Panoramic Dental Radiographs: Balancing Accuracy and Computational Efficiency. [PDF]

Diagnostics (Basel)
Yalım A, Aytugar E, Kalabalık F, Akdağ İ.   +3 more
europepmc   +1 more source

Chi dice ragna dice danno

L'article analitza les cites ecfràstiques de la Divina Comèdia en l'obra de Primo Levi i demostra la seva preponderància en la producció del químic-escriptor. Dos gravats de Gustave Doré, en particular, es van ancorar en la ment del jove Levi quan, de petit, va fullejar i va tornar a fullejar l'obra de l'artista francès, romanent com una icona ...
openaire   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

State Treaty on Gambling: Finally regulated

Wirtschaftsdienst, 2021
Justus Haucap
doaj   +1 more source

Do LLMs Play Dice? Exploring Probability Distribution Sampling in Large Language Models for Behavioral Simulation [PDF]

Jia Gu, Liang Pang, Huawei Shen, Xueqi Cheng   +3 more
openalex   +1 more source