Results 231 to 240 of about 1,558,397 (364)

Mixed U-Net: Segmentation of focal liver lesions using a hybrid 2D and 3D model. [PDF]

J Appl Clin Med Phys
Gao F, Hu Z, Xian J, Lu W.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Low power and high-speed quadrate node upset tolerant latch design using CNTFET. [PDF]

Sci Rep
Asiya S, S SK.
europepmc   +1 more source

Conformation of Polyalanine and Polyglycine Dications in the Gas Phase: Insight from Ion Mobility Spectrometry and Replica-Exchange Molecular Dynamics

, 2010
Florian Albrieux, F. Calvo, Fabien Chirot, Aleksey Vorobyev, Yury O. Tsybin, Valéria Lepère, Rodolphe Antoine, Jérôme Lemoine, Philippe Dugourd   +8 more
openalex   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Enhancing Surgical Planning with AI-Driven Segmentation and Classification of Oncological MRI Scans. [PDF]

Sensors (Basel)
Martinez Guillermo A, Zapata Pérez JF, Martinez-Alajarin J, Arévalo García A.   +3 more
europepmc   +1 more source

El Sr. encargado del Despacho del Ministerio de la Guerra ... me dice lo que sigue: ... D. Fernando VII por la gracia de Dios y por la constitucion ... a todos ... sabed que las cortes han decretado lo siguiente ... se aprueba ... la organizacion y fuerza de egercito permanente

, 2012
Capitanía General de Valencia y Murcia, Ildefonso Díez de Ribera Almodóvar, Carlos Francisco Cabrer   +2 more
openalex   +1 more source

DICER-ARGONAUTE2 Complex in Continuous Fluorogenic Assays of RNA Interference Enzymes

, 2015
M. Bernard, Leyu Wang, Souvenir D. Tachado   +2 more
openalex   +2 more sources

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

A novel sub-differentiable hausdorff loss combined with BCE for MRI brain tumor segmentation using UNet variants. [PDF]

Sci Rep
Visalakshi G, Mohan L.
europepmc   +1 more source