Results 251 to 260 of about 1,558,397 (364)

Scrap-SAM-CLIP: Assembling Foundation Models for Typical Shape Recognition in Scrap Classification and Rating. [PDF]

Sensors (Basel)
Bao G, Xia W, Wang H, Liao Z, Wu T, Zhou Y.   +5 more
europepmc   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

SALT: Introducing a framework for hierarchical segmentations in medical imaging using label trees. [PDF]

Sci Rep
Becker SS, Baldini G, Schmidt CS, Pollok OB, Pelka O, Kohnke J, Borys K, Friedrich CM, Schaarschmidt BM, Forsting M, Umutlu L, Haubold J, Nensa F, Hosch R.   +13 more
europepmc   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

LoRA-based methods on Unet for transfer learning in aneurysmal subarachnoid hematoma segmentation. [PDF]

BMC Med Imaging
Minoccheri C, Hodgman M, Ma H, Merchant R, Wittrup E, Williamson C, Najarian K.   +6 more
europepmc   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Topology preserving embedded network for PICC segmentation in pediatric X ray images. [PDF]

NPJ Digit Med
Yin X, Cheng K, Chen Z, Zhang P, Deng K, Deng H, Min X.   +6 more
europepmc   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

BoxCell: Leveraging SAM for Cell Segmentation with Box Supervision. [PDF]

Sci Rep
Tyagi AK, Mishra V, A P P, Mausam.
europepmc   +1 more source

The Raman fingerprint of cyclic conjugation: the case of the stabilization of cations and dications in cycloparaphenylenes

, 2016
Miriam Peña‐Álvarez, M. Carmen Ruiz Delgado, Mercedes Taravillo, Valentı́n G. Baonza, Juan T. López Navarrete, Paul J. Evans, Ramesh Jasti, Shigeru Yamago, Miklós Kertész, Juan Casado   +9 more
openalex   +2 more sources