Results 71 to 80 of about 134,287 (354)
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Unified Focal loss: Generalising Dice and cross entropy-based losses to handle class imbalanced medical image segmentation [PDF]
Comput. Medical Imaging Graph., 2021 Michael Yeung +3 more
semanticscholar +1 more source
Generalised Wasserstein Dice Score for Imbalanced Multi-class Segmentation using Holistic Convolutional Networks [PDF]
BrainLes@MICCAI, 2017 The Dice score is widely used for binary segmentation due to its robustness to class imbalance. Soft generalisations of the Dice score allow it to be used as a loss function for training convolutional neural networks (CNN).
Lucas Fidon +6 more
semanticscholar +1 more source
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
Sensors, 2019 A primary concern in a multitude of industrial processes is the precise monitoring of gaseous substances to ensure proper operating conditions. However, many traditional technologies are not suitable for operation under harsh environmental conditions ...
Andreas Och +7 more
doaj +1 more source
Genome biology, 2006 Research into the mechanism of RNA interference has seen immense progress over the past few years. Recent studies of the protein Dicer, a key enzyme in the process, have started to reveal how this single enzyme is targeted to different RNA-silencing pathways.
openaire +3 more sources
Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Generalized dice similarity measures for complex q-Rung Orthopair fuzzy sets and its application
Complex & Intelligent Systems, 2020 Complex q-rung orthopair fuzzy set (Cq-ROFS) is an extension of Complex fuzzy set, intuitionistic fuzzy set, Pythagorean fuzzy set, to cope with complicated and inconsistence information in the environment of fuzzy set theory with a wider domain.
Harish Garg, Zeeshan Ali, T. Mahmood
semanticscholar +1 more source
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source