Results 121 to 130 of about 75,724 (336)

Understanding the Role of Dicer in Astrocyte Development

PLOS ONE, 2015
The Dicer1 allele is used to show that microRNAs (miRNAs) play important roles in astrocyte development and functions. While it is known that astrocytes that lack miRNAs are dysregulated, the in vivo phenotypes of these astrocytes are not well understood. In this study, we use Aldh1l1-EGFP transgene, a marker of astrocytes, to characterize mouse models
Howng, Shen-Yi Bruce, Huang, Yong, Ptáček, Louis, Fu, Ying-Hui   +3 more
openaire   +7 more sources

Fabrication of GaN Nanowire Arrays via Electrodeless Photoelectrochemical Etching and its Application on UV Photodetectors

Advanced Materials Interfaces, EarlyView.
A local electric field‐enhanced electrodeless photoelectrochemical (ELPEC) etching method facilitates the anisotropic evolution of GaN nanostructures from nanocones to hollow nanocones and eventually to nanowire arrays. This rapid, mask‐free approach offers a practical and scalable route for fabricating ultraviolet photodetectors with improved ...
Chuhao Cai, Pengfei Yu, Yun Chen, Jiawei Xiao, Junjie Zhang, Li Ma, Maoxiang Hou, Xin Chen, Jian Gao, Ching‐Ping Wong, Meihong He, Wei Feng   +11 more
wiley   +1 more source

Caenorhabditis elegans RIG-I Homolog Mediates Antiviral RNA Interference Downstream of Dicer-Dependent Biogenesis of Viral Small Interfering RNAs. [PDF]

, 2017
Dicer enzymes process virus-specific double-stranded RNA (dsRNA) into small interfering RNAs (siRNAs) to initiate specific antiviral defense by related RNA interference (RNAi) pathways in plants, insects, nematodes, and mammals.
Gina Broitman-Maduro, Hongshan Jiang, Jinfeng Lu, Jing Zhong, Morris Maduro, Rui Lu, Shou-wei Ding, Stephanie R. Coffman, W. Ian Lipkin, Wan-Xiang Li, Xunyang Guo   +10 more
core   +3 more sources

Dicer regulates activation of the NLRP3 inflammasome

PLOS ONE, 2019
Inflammation plays a critical role in initiation of adaptive immunity, pathogen clearance and tissue repair. Interleukin (IL)-1β is a potent pro-inflammatory cytokine and therefore its production is tightly regulated: its secretion requires the assembly of a macromolecular protein complex, termed the inflammasome.
David M. Ojcius, Ardavan Jafari, Laxmi Yeruva, Christian W. Schindler, Ali A. Abdul-Sater   +4 more
openaire   +6 more sources

Deep Learning Analysis of Solid‐Electrolyte Interphase Microstructures in Lithium‐Ion Batteries

Advanced Materials Interfaces, EarlyView.
A transformer‐based deep learning model is developed for segmenting and analyzing high‐resolution TEM images of the solid‐electrolyte interphase (SEI) in lithium‐ion batteries. The model is trained on DFT‐based simulated images and predicts SEI grain and grain boundaries, revealing key microstructural features that govern ion transport and degradation.
Ishraque Zaman Borshon, Vahid Jabbari, Todd A. Kingston, Reza Shahbazian‐Yassar, Vitaliy Yurkiv   +4 more
wiley   +1 more source

The Etv2-miR-130a Network Regulates Mesodermal Specification

Cell Reports, 2015
MicroRNAs (miRNAs) are known to regulate critical developmental stages during embryogenesis. Here, we defined an Etv2-miR-130a cascade that regulates mesodermal specification and determination. Ablation of Dicer in the Etv2-expressing precursors resulted
Bhairab N. Singh, Yasuhiko Kawakami, Ryutaro Akiyama, Tara L. Rasmussen, Mary G. Garry, Wuming Gong, Satyabrata Das, Xiaozhong Shi, Naoko Koyano-Nakagawa, Daniel J. Garry   +9 more
doaj   +1 more source

High Transconductance on Thiophene‐Based Vertical Organic Electrochemical Transistors

Advanced Materials Technologies, EarlyView.
Vertical organic electrochemical transistors (vOECTs) fabricated with the organic mixed ionic‐electronic conductors poly(3‐hexylthiophene‐2,5‐diyl) (P3HT) and poly(3‐[2‐[2‐(2‐methoxyethoxy)ethoxy]ethyl]thiophene‐2,5‐diyl) (P3MEEET) demonstrate excellent performance, exhibiting high transconductance, large on‐currents, and high on/off ratios.
Marcos Luginieski, Henrique Frulani de Paula Barbosa, Ankush Kumar, Andreas Schander, Gregório Couto Faria, Björn Lüssem   +5 more
wiley   +1 more source

microRNAs calibrate T cell responses by regulating mTOR. [PDF]

, 2015
International ...
Marcais, A, Merkenschlager, M
core   +3 more sources

Diamond 2D/3D Printing Technology: Bringing Scintillating Performance to Functional Materials and Their Applications

Advanced Materials Technologies, EarlyView.
This review highlights advances in printing with nano‐ and microparticulate diamond for applications such as sensors, thermal management, machining tools, and biointerfaces. By covering screen, inkjet, microcontact, and 3D printing techniques, it outlines how diamond particles can be integrated into composite materials and functional devices, while ...
Simona Baluchová, Josephus G. Buijnsters   +1 more
wiley   +1 more source

Dicer and Drosha expression and response to Bevacizumab-based therapy in advanced colorectal cancer patients [PDF]

, 2013
PURPOSE: The miRNA-regulating enzymes Dicer and Drosha exhibit aberrant expression in several cancer types. Dicer and Drosha play a crucial role during the angiogenetic process in vitro and, for Dicer, in vivo. We aimed to investigate the potential role
Brunelli, C, Correale, P, Dell’Aquila, E, Falcone, A, Iuliani, M, Loupakis, F, Muda, A, Pantano, F, Perrone, G, Ratta, R, Riva, E, RUSSO, Antonio, Santini, D, Schiavon, G, Tonini, G., Vincenzi, B, Zoccoli, A   +16 more
core   +1 more source