Results 131 to 140 of about 89,653 (252)
The Journal of Clinical Pharmacology, Volume 66, Issue 5, May 2026.Abstract Bemnifosbuvir is a novel oral guanosine nucleotide prodrug with potent pan‐genotypic inhibitory activity against hepatitis C virus. In vitro studies assessing the inhibition or induction potential of bemnifosbuvir on the CYP450 and UGT1A1 enzymes demonstrated that bemnifosbuvir is a weak inducer and a reversible and time‐dependent inhibitor of
Xiao‐Jian Zhou +10 more
wiley +1 more source
Journal of the Science of Food and Agriculture, Volume 106, Issue 7, Page 4247-4255, May 2026.Abstract BACKGROUND The escalating prevalence of lifestyle‐ and aged‐related conditions, including diabetes, chronic inflammation, and cardiovascular disorders, underscores the urgent need for natural therapies. Such alternatives should offer reduced side effects compared to conventional pharmaceuticals while playing a proactive role in disease ...
Estefani Tavares Jansen +6 more
wiley +1 more source
MedComm, Volume 7, Issue 5, May 2026.Novel phenylalanine derivatives were identified as HIV‐1 capsid inhibitors. IC‐2i showed significant anti‐HIV‐1 activity at picomolar concentrations. ABSTRACT The HIV‐1 capsid (CA) is a validated antiviral target that plays critical roles in both the early and late stages of the viral life cycle.
Xujie Zhang +18 more
wiley +1 more source
The Impact of Differential Cost Sharing of Non-Steroidal Anti-Inflammatory Agents on the Use and Costs of Analgesic Drugs [PDF]
OBJECTIVE: To estimate the effect of differential cost sharing (DCS) schemes for non-steroidal anti-inflammatory drugs (NSAIDs) on drug subsidy program and beneficiary expenditures.
Adrian R. Levy +5 more
core
Studies on Regioselective Binding Mode of Steroid Molecules in Homology Modeled Cytochrome P450-2C11 [PDF]
, 2009 In this study, we investigated the regioselective binding mode of steroid molecules and structure requirements for steroid molecules for 16[alpha]-hydroxylation by Cytochrome P450-2C11.
Eiichi Akaho +3 more
core +1 more source
ChemistryOpen, Volume 15, Issue 5, May 2026.This review examines how hybrid modification strategies enhance the structural design and environmental performance of metal–organic frameworks (MOFs). It outlines key synthesis routes, functionalization approaches, and integration with complementary materials, highlighting advances in pollutant removal, sensing, and sustainable remediation.
Samar H. Elagamy +3 more
wiley +1 more source
Pediatric Anesthesia, Volume 36, Issue 5, Page 520-527, May 2026.ABSTRACT Background Procedures involving lung surgery in the pediatric population are relatively uncommon and tend to be centralized in a limited number of institutions. Anesthesia literature is also sparse. Aims To have a clear overview of frequency, underlying pathologies, ICU and hospital stay, anesthetic techniques, one lung ventilation, and ...
Rianne P. Wauters +2 more
wiley +1 more source
The comparison of the effect of pharmaceutical methods and ice pack on the reliefe of perineal pain after episiotomy in patient reffering to educational health centers of Alzahra- Tabriz,2005-6. [PDF]
Introduction: perineal pain is the most common women's problems in postpartum period. This problem has been found in %94 of the women who became episiotomy and it caused undesirable complications on mothers' physical and emotional health state and their ...
ایوان بقاء, ریحانه +3 more
core
PLANTS, PEOPLE, PLANET, Volume 8, Issue 3, Page 965-982, May 2026.Reusing organic waste materials, such as animal manure, as soil amendments reduces water and fertiliser demand, contributing to achieving the Sustainable Development Goals. However, organic wastes may contain contaminants of emerging concern (CECs), posing potential ecosystem and human health risks. Despite the importance of this issue, there is a lack
Felicity C. T. Elder +7 more
wiley +1 more source