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Australian and New Zealand Journal of Medicine, 1991
AbstractWe report five cases of biopsy‐proven hepatitis developing between six and 20 weeks after administration of diclofenac. In one patient jaundice had previously developed following use of ibuprofen. In another the clinical, biochemical and histopathological features were those of chronic active hepatitis and treatment with corticosteroids was ...
R W, Sallie +4 more
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AbstractWe report five cases of biopsy‐proven hepatitis developing between six and 20 weeks after administration of diclofenac. In one patient jaundice had previously developed following use of ibuprofen. In another the clinical, biochemical and histopathological features were those of chronic active hepatitis and treatment with corticosteroids was ...
R W, Sallie +4 more
openaire +2 more sources
Seminars in Arthritis and Rheumatism, 1985
The purpose in developing diclofenac sodium was to synthesize a nonsteroidal anti-inflammatory drug with high activity and outstanding tolerability. Factors considered were drug transport through biologic membranes, the atomic and spatial structure of the molecule, and the electronic structure.
openaire +3 more sources
The purpose in developing diclofenac sodium was to synthesize a nonsteroidal anti-inflammatory drug with high activity and outstanding tolerability. Factors considered were drug transport through biologic membranes, the atomic and spatial structure of the molecule, and the electronic structure.
openaire +3 more sources