Results 151 to 160 of about 50,511 (254)

Magnitude, Preventability, and Determinants of Adverse Drug Reactions Among Hospitalized Obstetric Patients in Ethiopia: A Prospective Observational Study

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Adverse drug reactions (ADRs) are an important and potentially preventable cause of morbidity among hospitalized obstetric patients, with implications for both maternal and fetal safety, yet evidence from low‐resource settings remains limited.
Getachew Yitayew Tarekegn, Endalemaw Tsegaw, Fisseha Nigussie Dagnew, Sisay Sitotaw Anberbr, Tilaye Arega Moges, Samuel Berihun Dagnew, Samuel Agegnew Wondm, Tigabu Eskeziya Zerihun, Abel Temeche Kassaw, Desalegn Addis Mussie   +9 more
wiley   +1 more source

Oridonin attenuates diclofenac-induced organ damage by suppressing endoplasmic reticulum stress and inflammasome activation. [PDF]

Front Toxicol
Al-Baldawi AH, Samaha MM, Zaghloul MS.
europepmc   +1 more source

European Interdisciplinary Guidelines on Pain Management in Acute Pancreatitis: UEG, EPC, EDS, ESDO, EAGEN, ESPGHAN, ESGAR, and ESPCG Evidence‐Based Recommendations

United European Gastroenterology Journal, Volume 14, Issue 5, June 2026.
ABSTRACT Pain is often the presenting symptom of acute pancreatitis (AP) and has a prognostic significance, with poorly treated pain affecting patient outcomes. Despite this, there are currently no international recommendations for pain management in patients admitted with AP.
Sanjay Pandanaboyana, Cecilie Siggaard Knoph, Louise Kuhlmann, Patrice Forget, Esther Pogatzki‐Zahn, Wei Huang, Stefanos Bonovas, Daniele Piovani, Isabelle Scheers, Karina Cárdenas‐Jaén, Sara Regner, Asbjorn Mohr Drewes, on behalf of European Pain in Acute Pancreatitis Multidisciplinary Group, Maissam Abu‐El‐Haija, Jana Aulenkamp, Frank Bodewes, Stefan Bouwense, Roberto Cannella, Gabriele Capurso, Guralp Ceyhan, Enrique de‐Madaria, Sarah De Lucia, Ana Dugic, Ekin Demir, Enrique Domínguez‐Muñoz, Lucia Guilabert, Pramod Kumar Garg, Cheryl Hartzell, Peter Hegyi, Nejo Joseph, James Lucocq, Giovanni Marchegiani, Alessio Marchetti, Soeren Marsmann, Etna Masip, Vivek Peddakota, Manu Nayar, Sara Nikolic, Hanna Sternby, Jayanta Samanta, Sandeep Siddhi, Ajith Siriwardena, Vikesh Singh, Søren Schou Olesen, Grzegorz Oracz, Davor Stimac, Michael Wilschanski, Heiko Witt, John Windsor   +48 more
wiley   +1 more source

Stage-Dependent Embryolethality of Diclofenac Sodium: Quantitative Assessment of Dose-Time Interaction and Critical Windows of Susceptibility in the In Ovo Chicken Embryo Model. [PDF]

Vet Sci
Kizilay H, Rama ST.
europepmc   +1 more source

The Effectiveness of Non‐Steroidal Anti‐Inflammatory Drugs for Pain Relief During Outpatient Intrauterine Device Insertion: A Systematic Review and Meta‐Analysis

Australian and New Zealand Journal of Obstetrics and Gynaecology, Volume 66, Issue 3, June 2026.
ABSTRACT Background Fear of procedural pain is a significant barrier to intrauterine device (IUD) uptake. Non‐steroidal anti‐inflammatory drugs (NSAIDs) are commonly used in IUD insertion for their analgesic and anti‐inflammatory properties; however, evidence for their effectiveness remains inconsistent.
Marita S. Bolic, Jack Ainsworth, Clare Heal, Natalie Drever   +3 more
wiley   +1 more source

Possible Diclofenac-Related Fulminant Toxic Epidermal Necrolysis: A Case Report. [PDF]

Cureus
Quintero Serrano N, Melo Trujillo OL.
europepmc   +1 more source

Pain management after elective caesarean section under neuraxial anaesthesia: an updated systematic review and procedure‐specific postoperative pain management (PROSPECT) recommendations

Anaesthesia, Volume 81, Issue 6, Page 819-839, June 2026.
Summary Introduction Elective caesarean section is a common and painful procedure. Uncontrolled pain following caesarean section can profoundly and negatively on a wide range of patient and healthcare‐centred outcomes. The aim of this systematic review was to update existing recommendations for postoperative pain management after elective caesarean ...
Gillian Crowe, Benjamin Atterton, Eva Roofthooft, Girish P. Joshi, Narinder Rawal, Christopher Wu, Axel R. Sauter, Marie‐Pierre Bonnet, Dominique Nuala Lucas, Marc Van de Velde, on behalf of the PROSPECT Working Group of the European Society of Regional Anaesthesia and Pain Therapy, Henrik Kehlet, Stephan M. Freys, Dileep N. Lobo, Eleni Moka, Neel Desai, Dario Bugada, Patricia Lavand'Homme, Helene Beloeil, Johan Raeder, Esther M. Pogatzki‐Zahn, Eric Albrecht, Geertrui Dewinter   +22 more
wiley   +1 more source

Structural and Functional Changes in Biological Systems of Wastewater Treatment Plants Induced by Bicyclic Non-Steroidal Anti-Inflammatory Drugs-A Review. [PDF]

Molecules
Jabłońska WM, Guzik U, Wojcieszyńska D.   +2 more
europepmc   +1 more source

KOH 5% solution versus diclofenac 3% for the treatment of actinic keratosis – Results from a three‐armed RCT

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 6, Page 1050-1058, June 2026.
In this RCT, KOH 5% demonstrated superior clinical success to diclofenac 3% and placebo at the end of treatment in patients with mild‐to‐moderate actinic keratosis and comparable long‐term efficacy to diclofenac. Its fast onset of efficacy and favourable tolerability make KOH a valuable treatment option in early‐stage actinic keratosis treatment ...
U. Reinhold, N. Leitz, R. Dominicus, E. L. Szabó, T. Dirschka, G. Popp, T. C. Fischer, N. Adamini, R. Ostendorf, M. Asefi, H. Durani, T. Hölting, U. Amann, F. Kreuziger, T. Assmann, H. Brüning, L. Freitag, K. Hoffmann, R. Gedschold   +18 more
wiley   +1 more source

Guiding a Diclofenac Sodium Dual-Release Sustained Formulation Development Through In Vitro-In Vivo Relationship Based on Physiologically Based Pharmacokinetics. [PDF]

Pharmaceutics
Wang Q, Guo P, Hu T, Li L, Zhu T, Pan Y, Xiang X, Wang J.   +7 more
europepmc   +1 more source