Employing diclofenac sodium as a novel therapeutic frontier for Staphylococcus epidermidis infections [PDF]
The spread of biofilm-forming multidrug-resistant pathogenic bacteria is an alarming public health issue requiring significant research. Drug repurposing is a novel approach to combating bacterial infections that is currently being studied.
Amal M. Abo-Kamar +4 more
doaj +2 more sources
Modulating morphine-induced conditioned place preference: The role of diclofenac sodium [PDF]
Morphine is known to induce strong reward-related behaviors, contributing to its high addiction potential. Non-steroidal anti-inflammatory drugs (NSAIDs), such as diclofenac sodium, have been suggested to modulate neuroinflammatory pathways involved in ...
Haneen Amawi +7 more
doaj +2 more sources
The anti-inflammatory effect of allopurinol and diclofenac in chicks’ model [PDF]
No studies have been conducted on the anti-inflammatory effect of allopurinol; eight-day old chicks are used. The aim of this paper was to study the anti-inflammatory action of allopurinol on a chemical pain model, both when administered alone or in ...
Maab A. Fadel, Khayrea A. Mustafa
doaj +1 more source
Coenzyme Q10 coadministration with diclofenac augmented impaired renal function in broiler chickens (Gallus gallus domesticus) [PDF]
Aim: This study aimed to investigate the effects of coenzyme Q10 (COQ10) and diclofenac coadministration on the hepatorenal function in broiler chickens (Gallus gallus domesticus).
Yasser Albadrany, Ahmed Naser
doaj +1 more source
Three methods for simultaneous estimation of diclofenac sodium and pridinol mesylate have been developed. First method is the application of the Q–analysis (absorbance ratio) method, the wavelengths selected were 265nm (isosbestic point) and 285nm (λmax ...
Hemn Khalid Qadir, Hemn A. Qader
doaj +3 more sources
Effect of Amoxicillin And Cefalexin on The Pharmacokinetics of Diclofenac Sodium in Healthy Volunteers [PDF]
Background: Studies investigating the effect of antibiotics on the pharmacokinetics of non-steroidal anti-inflammatory drugs are few. Such interaction could be clinically significant in conditions like diabetic nephropathy.
Shaima M. Ali +2 more
doaj +1 more source
Comparison of Intramuscular Versus Rectal Diclofenac Sodium in Post Caesarean Pain Relief
Objective: To compare the mean post-operative pain after intramuscular versus rectal Diclofenac Sodium in post-caesarean patients. Study Design: Quasi-experimental study. Place and Duration of Study: Department of Obstetrics & Gynaecology, Benazir
Beenish Altaf +5 more
doaj +1 more source
Ameliorative effect of N acetyl cysteine against diclofenac-induced oxidative stress, hematological and splenic toxicity in male rats [PDF]
Diclofenac sodium is one of the non-steroidal anti-inflammatory drugs that is used as anti-inflammatory, analgesic, and antipyretic. N-acetyl cysteine is an antioxidant and free radical scavenger used to combat oxidative stress-induced damage in various ...
sara kasem +5 more
doaj +1 more source
Aim:The aim of this study was to examine the basic mechanisms that play a role in the acute nephrotoxicity caused by diclofenac sodium.Materials and Methods:Only water was given to the control group; however, the diclofenac sodium group was group ...
Sinem Doğruyol +6 more
doaj +1 more source
TLC–Densitometry for Determination of Omeprazole in Simple and Combined Pharmaceutical Preparations
TLC combined with densitometry was used and chromatographic conditions developed to separate omeprazole and diclofenac sodium from their potential impurities.
Wioletta Parys, Alina Pyka-Pająk
doaj +1 more source

