Submucosal diclofenac for acute postoperative pain in third molar surgery: A randomized, controlled clinical trial [PDF]
Diclofenac sodium is a widely used nonsteroidal anti-inflammatory drug (NSAID) for relief of inflammatory pain. A recent formulation combines this drug with hydroxypropyl-β-cyclodextrin (HPβCD) to improve its solubility and to enable subcutaneous ...
Alkan Bozkaya T +18 more
core +3 more sources
Transforming Treatment: The Impact of Bariatric Surgery on Oral Drug Absorption
ABSTRACT Obesity represents a significant threat to global public health, with an estimated 16% of adults worldwide (2022) being classified as people with obesity, with a body mass index of 30 or more. Bariatric surgery is regarded as the most effective treatment option for people with obesity, with the three main types of bariatric surgery being ...
Danielle Wigg +3 more
wiley +1 more source
Corticosteroid transdermal delivery significantly improves arthritis pain and functional disability [PDF]
Arthritis is characterized by pain and functional limitation affecting the patients’ quality of life. We performed a clinical study to investigate the efficacy of a betamethasone valerate medicated plaster (Betesil) in improving pain and functional ...
AE Nelson +6 more
core +2 more sources
Abstract Objectives This systematic review investigated the efficacy of biologic factors in the surgical treatment of periodontal suprabony defects. Materials and Methods Three databases were searched to identify RCTs comparing open‐flap debridement (OFD) combined with biologic factors only, or combined with bone substitute, and/or barriers to the same
Carrie Chew +5 more
wiley +1 more source
P-576: Differential effects of selective cyclooxygenase-2 inhibitors on endothelial function in salt-induced hypertension [PDF]
In view of the ongoing controversy of potential differences in cardiovascular safety of selective COX-2 inhibitors (coxibs), we compared the effects of two different coxibs and a traditional NSAID on endothelial dysfunction, a well established surrogate ...
Camici, Giovanni +6 more
core
Rationale and evidence for the incorporation of heparin to the diclofenac epolamine medicated plaster [PDF]
The nonsteroidal anti-inflammatory drug (NSAID) diclofenac epolamine (DHEP) formulated as a topical patch has demonstrated efficacy and safety in the localized treatment of acute pain from minor strains, sprains, and contusions, and for epicondylitis and
Alessandro Nencioni +16 more
core +1 more source
Analgesic effects of platelet‐rich fibrin (PRF): A systematic review
Abstract Background Platelet‐rich fibrin (PRF), a second‐generation autologous platelet concentrate, has gained significant interest for its anti‐inflammatory and regenerative characteristics. While its role in tissue healing is well‐recognized, the analgesic potential of PRF remains under‐investigated.
Nathan E. Estrin +6 more
wiley +1 more source
This paper describes a degradation study of the anti-inflammatory sodium diclofenac in aqueous medium using an electro-chemical flow reactor with a gas diffusion electrode as cathode. Two degradation processes were compared: by H2O2 electro-generated and
Robson S. Rocha +3 more
doaj +1 more source
A stereological study of the effects of mercury inhalation on the cerebellum [PDF]
Mercury in the environment that arises from organic and inorganic sources can cause irreversible damage to the nervous system. Toxicity may be direct or may arise from interactions with other metals in the environment.
Akgul, Hayati Murat +4 more
core +1 more source
Ultrasound‐guided, minimally invasive, biceps brachii tenotomy in a standing horse
Abstract Objective To describe the long‐term outcome of a horse that underwent a standing, ultrasound‐guided, minimally invasive, biceps brachii tenotomy. Study design Case report. Animal A 17‐year‐old Tennessee Walking Horse gelding. Methods The horse had a chronic, severe, lameness localized to the left shoulder region.
Guilherme F. Marques +4 more
wiley +1 more source

