Results 41 to 50 of about 20,321 (243)

EFFECT OF CRYOPRESERVED PLACENTA EXTRACT ON SOME BIOCHEMICAL INDICES OF THERAPEUTIC EFFICIENCY AND TOXICITY OF DICLOFENAC SODIUM IN ADJUVANT-INDUCED EXPERIMENTAL ARTHRITIS

open access: yesФармация и фармакология (Пятигорск), 2021
Non-steroidal anti-inflammatory drugs are among the top requested ones in the clinic of internal medicine. However, these drugs are associated with a wide range of adverse reactions involving a number of organs and systems, in particular the ...
F. V. Hladkykh   +4 more
doaj   +1 more source

The In Vitro Transgenic Rodent Assay in Primary MutaMouse Hepatocytes Compared to the Mammalian Cell Gene Mutation Assay Using the HPRT Gene

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
ABSTRACT Gene mutations can be detected in mammalian cells in vitro using indicator genes such as the hypoxanthine‐guanine‐phosphoribosyltransferase (HPRT) gene. These assays have been adopted as OECD test guidelines (TG, e.g., OECD TG no. 476) and are used for regulatory purposes.
Alina Göpfert   +5 more
wiley   +1 more source

Modulating Effect of Vitamin D on iNOS, PCNA and a-SMA Expression Against Diclofenac Sodium Induced Gastric Injury in Rats

open access: yesIndonesian Biomedical Journal, 2020
BACKGROUND: Diclofenac sodium is a nonsteroidal anti-inflammatory prescription, widely used in the management of many inflammatory diseases but the side effects limiting its clinical use. The present work was carried out to detect the ameliorative effect
Sahar Youssef
doaj   +1 more source

Performance of HDTMA-Br-Modified Indonesian Zeolite as a Drug Carrier Candidate for Diclofenac Sodium

open access: yesJurnal Kimia Sains dan Aplikasi, 2021
Diclofenac sodium is a non-steroidal anti-inflammatory drug with a relatively short release time. This short release time promotes a more frequent drug consumption and could lead to side effects in the stomach, e.g., gastrointestinal disorders ...
Khafidhotun Naimah   +3 more
doaj   +1 more source

Microengineering the Liver: Strategies for Constructing Functional Liver‐on‐a‐Chip Devices

open access: yesExploration, EarlyView.
This review summarizes recent advances in liver‐on‐a‐chip (LOC) technologies, including fabrication strategies and functional integration approaches, and discusses their promising applications in drug screening and related biomedical fields. ABSTRACT Reliable in vitro liver models are indispensable for researching liver diseases and developing ...
Jie Wang   +7 more
wiley   +1 more source

NSAIDs and Bleeding in Periodontal Surgery [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2014
Aim: To evaluate and compare the clinical effects of ibuprofen and diclofenac sodium on bleeding during periodontal surgery. Materials and Methods: Thirteen medically healthy men and women of mean age 37.5±17.67 (mean age± standard deviation) were ...
Sanyuktha Shetty   +5 more
doaj   +1 more source

A rare case of perineal neuralgia treated with ultrasound‐guided nerve block combined with water separation

open access: yesIbrain, Volume 11, Issue 1, Page 106-111, Spring 2025.
A middle‐aged man presented with a right indirect inguinal hernia in November 2020 and underwent laparoscopic high ligation of the right hernial sac. Intermittent acupuncture‐like pain in the skin of the right scrotum and medial thigh occurred 1 month after surgery and lasted for 6 months. Under ultrasound guidance, ilioinguinal nerve and genitofemoral
Yong Wang   +4 more
wiley   +1 more source

Pharmacokinetics Interaction of Non-Steroid Anti Inflammatory Drugs to 99mTc-MDP Radiopharmaceuticals for Bone Imaging and Its Biodistribution

open access: yesAtom Indonesia, 2018
99mTc-MDP has been developed as a radiopharmaceutical for bone imaging in nuclear medicine. A drug therapy can alter the pharmacokinetic profiles and biodistribution patterns of radiopharmaceuticals.
I. Mahendra   +3 more
doaj   +1 more source

Preparation and Characterization of Chitosan/LDH Composite Membranes for Drug Delivery Application

open access: yesMembranes, 2023
In this study, composite membranes based on chitosan (CS), layered double hydroxide (LDH), and diclofenac were prepared via dispersing of LDH and diclofenac (DCF) in the chitosan matrix for gradual delivery of diclofenac sodium.
Elena-Ruxandra Radu   +4 more
doaj   +1 more source

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