Results 81 to 90 of about 20,321 (243)
ABSTRACT This study presents the green synthesis of silver (Ag‐NPs) and iron nanoparticles (Fe‐NPs) using aqueous leaf extract of Grewia optiva as a natural reducing and stabilizing agent. The extract was prepared using a Kjeldahl apparatus under controlled heating. Nanoparticle synthesis was optimized by varying pH, temperature, and salt concentration,
Muhammad Salman Khan +8 more
wiley +1 more source
Diclofenac Sodium Treatment Ameliorates Extrapancreatic Organ Injuries in a Murine Model of Acute Pancreatitis Induced by Caerulein [PDF]
Özlem Özer Çakır, Sıddıka Fındık
openalex +1 more source
Unraveling Chronic Pain: From Mechanisms and Risks to Diagnosis and Treatment
Chronic pain arises through distinct molecular pathways categorized into nociceptive, neuropathic, and nociplastic types. Nociceptive pain begins with TRP channel activation in peripheral nociceptors, signaling via Aδ‐ and C‐fibers through the spinal dorsal horn and spinothalamic tracts to the brain, regulated by descending inhibition and involving ...
Xiaofeng Dai +3 more
wiley +1 more source
Therapeutic index, a drug safety parameter, is comparation between the dose at which 50% animals are dead (LD50) and the dose at which 50% animals exhibit the specified effect (ED50).
Donaliazarti +3 more
doaj +1 more source
This review article provides a comprehensive exploration of the synergistic integration of molecular dynamics (MD) simulations and metal–organic frameworks (MOFs) to advance the design and optimization of nanoscale drug delivery systems (DDSs). We believe this work will be of significant interest to researchers in nanomedicine, computational biology ...
Jiahao Xu +11 more
wiley +1 more source
Introduction: Pain is a significant problem globally. Ehretia laevis Roxb has pain-relief and anti-inflammatory properties. Cyclooxygenase (COX) is responsible for the production of prostaglandins, which control pain and inflammation.
Rushikesh Anil Thakre +3 more
doaj +1 more source
Background: In general, patients with osteoarthritis require long live treatments, especially anti-infammatory drugs. Non steroidal anti infammatory drugs are mostly follow by some side effects such as dyspepsia and gastrointestinal bleeding.
Nyoman Kertia +3 more
doaj +1 more source
In Silico, In Vitro, and In Vivo Antinociceptive Potential of S‐Naproxen Derivatives
Selected naproxen derivatives were investigated for their antinociceptive effects, using in vitro (COX‐I/COX‐II antagonistic effect), in vivo (acetic acid and hot plate assay), and in silico (molecular simulation studies) approaches. The COX inhibition studies revealed that the maximum percent effect exhibited by GMO‐I‐111a 96.01 and 92% against COX‐2 ...
Ubaidullah +13 more
wiley +1 more source
The presence of TiO2 in Fricke dosimetric systems introduces complex interferences under gamma irradiation. Adsorption of Fe2+/Fe3+ ions, coupled with radiolytic and surface‐mediated processes, alters redox equilibria and apparent absorbed dose values, highlighting critical challenges in chemical dosimetry applied to heterogeneous radiolytic ...
William Villacis +4 more
wiley +1 more source
Two prepared adsorbents, namely, calcined ZnAl-layered double hydroxide and K10 montmorillonite intercalated with cetyltrimethyl-ammonium bromide cations are used in diclofenac sodium adsorption under the batch reactor operations. The pseudo-second-order
Nadia Boukhalfa +2 more
doaj +1 more source

