Results 81 to 90 of about 20,321 (243)

Biogenic Synthesis of Silver and Iron Nanoparticles Derived From Grewia Optiva Leaf Extract: A Novel Approach for Antidiabetic, Anticoagulant and Anti‐Inflammatory Therapies

open access: yesInternational Journal of Chemical Kinetics, Volume 58, Issue 4, Page 159-174, April 2026.
ABSTRACT This study presents the green synthesis of silver (Ag‐NPs) and iron nanoparticles (Fe‐NPs) using aqueous leaf extract of Grewia optiva as a natural reducing and stabilizing agent. The extract was prepared using a Kjeldahl apparatus under controlled heating. Nanoparticle synthesis was optimized by varying pH, temperature, and salt concentration,
Muhammad Salman Khan   +8 more
wiley   +1 more source

Unraveling Chronic Pain: From Mechanisms and Risks to Diagnosis and Treatment

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Chronic pain arises through distinct molecular pathways categorized into nociceptive, neuropathic, and nociplastic types. Nociceptive pain begins with TRP channel activation in peripheral nociceptors, signaling via Aδ‐ and C‐fibers through the spinal dorsal horn and spinothalamic tracts to the brain, regulated by descending inhibition and involving ...
Xiaofeng Dai   +3 more
wiley   +1 more source

Nilai Indeks Terapi Ekstrak Etanol Daun Dewa {Gynura pseudochina (Lour.) DC} dan Natrium Diklofenak pada Tikus Model Inflamasi

open access: yesMajalah Kedokteran Bandung, 2012
Therapeutic index, a drug safety parameter, is comparation between the dose at which 50% animals are dead (LD50) and the dose at which 50% animals exhibit the specified effect (ED50).
Donaliazarti   +3 more
doaj   +1 more source

The Application of Metal–Organic Frameworks as Drug Delivery Systems: From the Perspective of Molecular Dynamics Simulations

open access: yesMedComm, Volume 7, Issue 4, April 2026.
This review article provides a comprehensive exploration of the synergistic integration of molecular dynamics (MD) simulations and metal–organic frameworks (MOFs) to advance the design and optimization of nanoscale drug delivery systems (DDSs). We believe this work will be of significant interest to researchers in nanomedicine, computational biology ...
Jiahao Xu   +11 more
wiley   +1 more source

Assessment of Comparative COX-1 and COX-2 Inhibition Efficacy of Ehretia Laevis Roxb. (Khandu Chakka/Ajan Vruksha) Leaves versus Diclofenac Sodium: An In-vitro Study

open access: yesJournal of Clinical and Diagnostic Research
Introduction: Pain is a significant problem globally. Ehretia laevis Roxb has pain-relief and anti-inflammatory properties. Cyclooxygenase (COX) is responsible for the production of prostaglandins, which control pain and inflammation.
Rushikesh Anil Thakre   +3 more
doaj   +1 more source

Perubahan kadar hemoglobin akibat terapi kurkuminoid ekstrak rimpang kunyit dibandingkan natrium diklofenak pada penderita osteoartritis

open access: yesJurnal Gizi Klinik Indonesia, 2011
Background: In general, patients with osteoarthritis require long live treatments, especially anti-infammatory drugs. Non steroidal anti infammatory drugs are mostly follow by some side effects such as dyspepsia and gastrointestinal bleeding.
Nyoman Kertia   +3 more
doaj   +1 more source

In Silico, In Vitro, and In Vivo Antinociceptive Potential of S‐Naproxen Derivatives

open access: yesChemistryOpen, Volume 15, Issue 4, April 2026.
Selected naproxen derivatives were investigated for their antinociceptive effects, using in vitro (COX‐I/COX‐II antagonistic effect), in vivo (acetic acid and hot plate assay), and in silico (molecular simulation studies) approaches. The COX inhibition studies revealed that the maximum percent effect exhibited by GMO‐I‐111a 96.01 and 92% against COX‐2 ...
Ubaidullah   +13 more
wiley   +1 more source

Interference of TiO2 in Fricke Dosimetry: Adsorption Mechanisms and Dose Measurement Challenges under Gamma Irradiation

open access: yesChemistryOpen, Volume 15, Issue 4, April 2026.
The presence of TiO2 in Fricke dosimetric systems introduces complex interferences under gamma irradiation. Adsorption of Fe2+/Fe3+ ions, coupled with radiolytic and surface‐mediated processes, alters redox equilibria and apparent absorbed dose values, highlighting critical challenges in chemical dosimetry applied to heterogeneous radiolytic ...
William Villacis   +4 more
wiley   +1 more source

Synthesis and characterization of ZnAl-layered double hydroxide and organo-K10 montmorillonite for the removal of diclofenac from aqueous solution

open access: yesAdsorption Science & Technology, 2017
Two prepared adsorbents, namely, calcined ZnAl-layered double hydroxide and K10 montmorillonite intercalated with cetyltrimethyl-ammonium bromide cations are used in diclofenac sodium adsorption under the batch reactor operations. The pseudo-second-order
Nadia Boukhalfa   +2 more
doaj   +1 more source

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