Results 201 to 210 of about 178,961,087 (289)

A Phase I study of the pharmacokinetics (PK), bioavailability, dose proportionality, safety, and tolerability of topiramate injection compared to Oral topiramate in healthy adult participants

Epilepsia, EarlyView.
Abstract This Phase I study evaluated the safety, tolerability, and pharmacokinetics of a 30‐min topiramate injection (intravenous [IV] TPM) infusion compared with oral topiramate (oral TPM) in healthy adult participants. In this randomized, open‐label, dose escalation, crossover study with 37 healthy participants received single doses of 50, 100, or ...
Adeboye O. Bamgboye, James C. Cloyd, Bernard D. King, Lisa D. Coles   +3 more
wiley   +1 more source

Clinical pathway data engineering framework (CPDEF): a reproducible methodology for constructing machine learning-ready case-mix datasets from hospital information systems. [PDF]

MethodsX
Nugroho S, Ginardi RVH, Purnama IKE.
europepmc   +1 more source

Silence around SUDEP and its impact on caregivers of individuals with developmental and epileptic encephalopathies: An international survey

Epilepsia Open, EarlyView.
Abstract Objective Sudden Unexpected Death in Epilepsy (SUDEP) is the leading cause of epilepsy‐related mortality, particularly in individuals with Developmental and Epileptic Encephalopathies (DEEs). The goal of this work is to assess SUDEP‐related knowledge, information practices, emotional and psychological impact, and the use of preventive measures
José Ángel Aibar, Ana Cantó Martínez, David Alarcón Alarcón, Eulalia Turón‐Viñas, Rima Nabbout, Isabella Brambilla, Franck Kalume, Danielle Andrade, Simona Giorgi   +8 more
wiley   +1 more source

An integrated case-based leptospirosis surveillance dataset with environmental context from a tropical coastal city in Indonesia, 2018-2023. [PDF]

Data Brief
Adhinugraha K, Ciptaningtyas VR, Hapsari R, Wisudiawan GAA, Lestari WD, Hutapea JBMP, Pakpahan SB, Taniar D.   +7 more
europepmc   +1 more source

A Knowledge‐Augmented Wearable System for Interpretable Plant Health Monitoring

FlexTech, EarlyView.
We present K‐Wear, a knowledge‐augmented wearable system for interpretable plant health monitoring. A soft multimodal sensing platform continuously captures spectral, humidity, and temperature signals from plant leaves, which are processed through a knowledge‐guided large language model reasoning framework to generate mechanistic diagnoses and ...
Xingxing Dong, Yihan Luo, Qin Jiang, Jie Ye, Yihui Fan, Menghao Pu, Zisheng Zong, Guoqiang Xu, Han Ding, Zhigang Wu   +9 more
wiley   +1 more source

Single-Pixel Tactile Skin via compressive sampling. [PDF]

Commun Eng
Slepyan A, Xing L, Zhang R, Thakor N.
europepmc   +1 more source

Citrus Essential Oils in Food Safety and Health: Advances in AI‐Assisted Authentication, Antimicrobial Applications, Sustainable Extraction, and Regulatory Translation

Food Safety and Health, EarlyView.
Citrus essential oils combine sustainable extraction, AI‐assisted authentication, multi‐omics profiling, antimicrobial activity, and regulatory safety to enhance food quality, detect adulteration, and promote consumer health, and support intelligent, sustainable food systems through innovative industrial applications and circular bioeconomy strategies.
Md. Hassan Bin Nabi, Liza Akter, Yusuf Chowdhury, Mohima Akther Any, Nazmul Islam, Erni Sofia Murtini, Nurul Huda, Wahidu Zzaman   +7 more
wiley   +1 more source

Re-curating a 90-year ecological data collection from an Australian arid zone enclosure according to FAIR principles. [PDF]

Sci Data
Specht A, Fittock M, Karsdorp W, Singh Ramesh A, Sanchez Gonzalez J, Guru SM.   +5 more
europepmc   +1 more source

Volatility Formation in Dairy Futures: Fundamentals, Public Information, and Processing Ambiguity

Journal of Futures Markets, EarlyView.
ABSTRACT Class III milk futures cash‐settle to an administered price based on weekly component prices, creating a predictable within‐month flow of settlement‐relevant information. This paper studies drivers of cross‐month variation in realized volatility in this formula‐settled market.
Xiaodong Du
wiley   +1 more source

Dissecting the angiogenic mechanism of pachychoroid polypoidal choroidal vasculopathy

iMeta, EarlyView.
A prognosis‐oriented classification system was established to distinguish Pachy PCV from Non‐pachy PCV using a large multicenter dataset. Comparative plasma multi‐omics profiling of Pachy PCV, Non‐pachy PCV, and normal controls revealed unique upregulation of the fluid shear stress and atherosclerosis (FSS‐AS) and HIF‐1 signaling pathways in Pachy PCV.
Xinyu Zhao, Tiantian Cheng, Wenfei Zhang, Xingwang Gu, Qing Zhao, Yaning Chen, Lihui Meng, Jiaqi Zhang, Bintao Qiu, Lili Li, Shiyu Cheng, Zicheng Wang, Chuting Wang, Yuelin Wang, Zuyi Yang, Zhengming Shi, Ye Guo, Shengzhi Liu, Youxin Chen   +18 more
wiley   +1 more source