Results 71 to 80 of about 165,090 (316)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Reflections from the President
Victoria University Law and Justice Journal, 2012 DICTUM editors Taha Khan, Ashleigh Kemp and Julia Swift interview Christopher Maxwell, President of the Court of Appeal, Supreme Court of Victoria.
Christopher Maxwell
doaj +1 more source
Mr. Justice Black, Constitutional Review, and the Talisman of State Action [PDF]
, 1965 In an endorsement of Justice Black’s dissent in Bell v. Maryland, this work argues in favors of Black’s interpretation of the state action requirement and attempts to make sense of Black’s understanding in other cases where he found state action in ...
Van Alstyne, William W.
core +4 more sources
Thorax, 2015 Anand Shah and Scott R Henderson (AS and SRH): a 72-year-old retired male physician was referred with poorly controlled asthma, necessitating oral glucocorticoid therapy.
Scott R. Henderson +6 more
semanticscholar +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Book Review: Leaving Rules that Enforce Preconception
Grounded Theory Review: An International Journal, 2014 Barney Glaser (2013) No preconceptions – The grounded theory dictum. Mill Valley, CA: Sociology Press Given that the dictum of no preconception is not new in GT, why did Glaser focus his attention so much on it to write a whole book on this topic ...
Pernilla Pergert
doaj +2 more sources
Mirabile Dictum! The Case for \u27Unnecessary\u27 Constitutional Rulings in Civil Rights Damages Actions [PDF]
, 1999 This article contends that, for purposes of settling the law, courts entertaining civil rights lawsuits doomed to fail on grounds of qualified immunity should presumably address the question whether the complaint pleads a viable claim that the defendant ...
Greabe, John M.
core +2 more sources
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
, 2007 We explore nonlocally modified models of gravity, inspired by quantum loop corrections, as a mechanism for explaining current cosmic acceleration.
C. M. Will +4 more
core +2 more sources
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source