Results 1 to 10 of about 397,473 (258)

Patient Experiences with Relapsing–Remitting and Primary Progressive Multiple Sclerosis: Development of a Conceptual Model to Inform Clinical Outcome Assessment Evaluation [PDF]

Neurology and Therapy
Introduction Multiple sclerosis (MS) is an autoimmune-mediated neurodegenerative disorder. The United States Food and Drug Administration recommends using clinical outcome assessments (COAs) to measure concepts that matter to patients in clinical trials ...
Ekin Seçinti, Louise Barrett, Laure Delbecque, Margaret Hoyt, Zahava Rosenberg-Yunger, Jessica Baldasaro, Kailynn Schmidt, Jessica Mills, Stefan Cano, Chetan Gandhy, Sarah E. Curtis   +10 more
doaj   +2 more sources

Conceptualising the experience of having TB: a global qualitative study [PDF]

IJTLD Open
BACKGROUND: TB and aspects of its treatment are known to impair health-related quality of life, but data are lacking on how pulmonary TB is experienced from the standpoint of affected individuals.
D. Oberdhan, M. Hill, A. Gillman, N. McGale, J. Dandy, T. Abdullaev, M. Dara   +6 more
doaj   +2 more sources

Modus tollens with respect to uninorms: U-Modus Tollens

International Journal of Approximate Reasoning, 2020
In fuzzy logic and approximate reasoning the inference rule given by the Modus Tollens usually derives into an inequality involving three logical operators: a conjunction, an implication function and a negation. Until now, in this scenario the conjunction has been commonly modeled by a t-norm, but recently the possibility of using a more general ...
Isabel Aguilo, Juan Vicente Riera, Joan Torrens   +2 more
exaly   +4 more sources

Profitability of Photovoltaic and Energy Storage System in a Foundry Plant [PDF]

Archives of Foundry Engineering, 2023
The article presents a case study on the effectiveness of photovoltaic farm and battery energy storage in one of the Polish foundries. In the study, we consider two investment options: stand-alone PV farm of 1MWp and the farm together with battery energy
A. Stawowy, R. Wrona, M. Sawczuk, D. Lasek   +3 more
doaj   +1 more source

Establishing clinically meaningful within-individual improvement thresholds for eight patient-reported outcome measures in people with relapsing-remitting multiple sclerosis

Journal of Patient-Reported Outcomes, 2023
Background As disease-modifying therapies do not reverse the course of multiple sclerosis (MS), assessment of therapeutic success involves documenting patient-reported outcomes (PROs) concerning health-related quality of life, disease and treatment ...
Nupur Greene, Stéphane Quéré, Denise P. Bury, Flora Mazerolle, Manal M’Hari, Angély Loubert, Antoine Regnault, Keiko Higuchi   +7 more
doaj   +1 more source

Development of the Myasthenia Gravis (MG) Symptoms PRO: a case study of a patient-centred outcome measure in rare disease

Orphanet Journal of Rare Diseases, 2021
Background Myasthenia gravis (MG) is a chronic autoimmune neuromuscular disease, characterised by fluctuating muscle weakness which makes it challenging to assess symptom severity.
Sophie Cleanthous, Ann-Christin Mork, Antoine Regnault, Stefan Cano, Henry J. Kaminski, Thomas Morel   +5 more
doaj   +1 more source

Development and psychometric evaluation of the assessment of self-injection questionnaire: an adaptation of the self-injection assessment questionnaire

Health and Quality of Life Outcomes, 2020
Background Patient-reported outcome (PRO) instruments provide robust and effective means of evaluating patients’ treatment experience; however, none adequately cover experience using self-injection devices with enhanced features, such as an ...
Farrah Pompilus, Anna Ciesluk, Sara Strzok, Valerie Ciaravino, Kristina Harris, Boglarka Szegvari, Irina Mountian, Sophie Cleanthous, Juliette Meunier   +8 more
doaj   +1 more source

A Mixed-Methods Study to Better Measure Patient-Reported Pain and Fatigue in Soft Tissue Sarcoma

Oncology and Therapy, 2023
Introduction Pain and fatigue are commonly reported by patients with soft tissue sarcoma (STS) as distressing symptoms, yet no patient-reported outcome (PRO) measures have been validated or developed specifically for STS.
Louise Barrett, Emma Elliott, Maarten Voorhaar, Anders Ingelgård, Ingolf Griebsch, Brendon Wong, Jessica Mills, Phoebe Heinrich, Stefan Cano   +8 more
doaj   +1 more source

Development and content validation of the Symptoms Evolution of COVID-19: a patient-reported electronic daily diary in clinical and real-world studies

Journal of Patient-Reported Outcomes, 2022
Background At the onset of the COVID-19 pandemic, there was limited understanding of symptom experience and disease progression. We developed and validated a fit-for-purpose disease-specific instrument to assess symptoms in patients with COVID-19 to ...
Diana Rofail, Nadine McGale, Joseph Im, Alissa Rams, Krystian Przydzial, Vera Mastey, Sumathi Sivapalasingam, Anna J. Podolanczuk   +7 more
doaj   +1 more source

Patient experience of symptoms and impacts of COVID-19: a qualitative investigation with symptomatic outpatients

BMJ Open, 2022
Objectives There is little in-depth qualitative evidence of how symptoms manifest themselves in outpatients with COVID-19 and how these in turn impact outpatients’ daily lives.
Anna J Podolanczuk, Vera Mastey, Diana Rofail, Nadine McGale, Alissa Rams, Krystian Przydzial, Sumathi Sivapalasingam, Patrick Marquis   +7 more
doaj   +1 more source