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DNA polymerase of Dictyostelium discoideum
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1976Only one molecular weight species of DNA polymerase was found in different developmental stages of the eukaryotic microorganism Dictyostelium discoideum. The molecular weight of this DNA polymerase is estimated to be about 127 000 by sucrose gradient centrifugation. The enzyme is present in all stages of growth and development, including dormant spores.
Edward F. Rossomando+2 more
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CHEMOATTRACTANT SIGNALING IN DICTYOSTELIUM DISCOIDEUM [PDF]
▪ Abstract Dictyostelium is an accessible organism for studies of signaling via chemoattractant receptors. Chemoattractant-mediated signaling events and components are reviewed and presented as a series of connected modules, including excitation, inhibition, G protein–independent responses, early gene expression, inositol lipids, PH domain-containing
Pablo A. Iglesias+3 more
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Pacemaker mutants of Dictyostelium discoideum
Developmental Biology, 1974Abstract In this paper, I report measurements of the time intervals between aggregation waves in two morphogenetic mutants of Dictyostelium discoideum NC-4. The mutants both have abnormal wave periodicity and their abnormalities are interpreted in terms of defects in the cellular properties which underlie wave propagation.
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The Inositolcycle of Dictyostelium Discoideum
1990Transmembrane signal transduction is characterized largely by the interaction between its components: ligand, receptor on the surface of cells, G-protein subunits at the inner face of the plasma membrane, and effector enzymes. The effector enzymes may vary widely depending on the organism and the ligand, and include adenylate cyclase, guanylate cyclase,
Richard Draijer+9 more
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Phagosomal Proteins of Dictyostelium discoideum
Journal of Eukaryotic Microbiology, 1997ABSTRACT. In recognizing food particles, Dictyostelium cell‐surface molecules initiate cytoskeletal rearrangements that result in phagosome formation. After feeding D. discoideum cells latex beads, early phagosomes were isolated on sucrose step gradietns.
Rezabek, Betsy L.+3 more
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Rho Signaling in Dictyostelium discoideum
2016Small GTPases of the Rho family are ubiquitous molecular switches involved in the regulation of most actin cytoskeleton dependent processes and many other processes not directly linked to actin. D. discoideum is a well-established model organism for studies of the actin cytoskeleton and its regulation by signal transduction pathways. D.
Rivero Crespo, Francisco+1 more
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Antisense RNA inactivation of myosin heavy chain gene expression in Dictyostelium discoideum.
Science, 1987The role of myosin in the contraction of striated muscle cells is well known, but its importance in nonmuscle cells is not yet clear. The function of myosin in Dictyostelium discoideum has been investigated by isolating cells which specifically lack ...
D. Knecht, W. Loomis
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Mutants in Phototaxis of Dictyostelium discoideum
Nature, 1970ONE of the more interesting behavioural characteristics of the cellular slime mould, Dictyostelium discoideum, involves the concerted migration of thousands of amoebae in a pseudoplasmodium or slug towards light. There have been several studies of the phenomenon, and the action spectrum for phototaxis has been shown1–4 to have peaks at 425 and 550 nm ...
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Modelling Dictyostelium discoideum Morphogenesis: the Culmination
Bulletin of Mathematical Biology, 2002The culmination of the morphogenesis of the cellular slime mould Dictyostelium discoideum involves complex cell movements which transform a mound of cells into a globule of spores on a slender stalk. We show that cyclic AMP signalling and differential adhesion, combined with cell differentiation and slime production, are sufficient to produce the ...
Athanasius F. M. Marée, Paulien Hogeweg
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Calcium Signalling in Dictyostelium discoideum
2022A thesis submitted in total fulfilment of the requirements for the degree of Doctor of Philosophy to the Department of Microbiology, Anatomy, Physiology and Pharmacology, School of Agriculture, Biomedicine and Environment, La Trobe University, Victoria, Australia.
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