Results 121 to 130 of about 7,840 (177)
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Dicyclohexylcarbodiimide — An inhibitor of oxidative phosphorylation

Biochemical and Biophysical Research Communications, 1966
Abstract This communication reports some of the properties of a new inhibitor of oxidative phosphorylation, DCCD ∗ , whose mode of action is similar to oligomycin and aurovertin (Lardy et al., 1958). Low titres of DCCD inhibit the ccupled respiration of mitochondria and the ATP-driven partial reactions of oxidative phosphorylation catalysed by ETPH.
R B, Beechey   +3 more
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Sensitivity of methanogenic bacteria to dicyclohexylcarbodiimide

Canadian Journal of Microbiology, 1982
Methanospirillum hungatei strains GP1 and JF1 when exposed to the adenosinetriphosphatase inhibitor N,N′-dicyclohexylcarbodiimide experienced a marked decline in growth rates, methane synthesis activities, and intracellular ATP concentrations. Although growth was inhibited, the intracellular ATP concentrations of all other methanogens tested were ...
Sprott, G., Jarrell, K.
openaire   +3 more sources

Dicyclohexylcarbodiimide-binding sites in the myelin proteolipid

Neurochemical Research, 1984
Dicyclohexylcarbodiimide (DCCD), an inhibitor of proton translocation, has been shown to bind preferentially to the myelin proteolipid and to inhibit proton movement in liposomes containing the proteolipid (Lin, L. and Lees, M. 1982. Proc. Natl. Acad. Sci. USA 79:941-945). In the present study the location of the DCCD-binding site(s) in the sequence of
L F, Lin, M B, Lees
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Dicyclohexylcarbodiimide as inducer of mitochondrial Ca2+ release

Journal of Bioenergetics and Biomembranes, 1990
The effect of the alkylating reagent dicyclohexylcarbodiimide (DCCD) on mitochondrial Ca2+ content was studied. The results obtained indicate that DCCD at a concentration of 100 microM induces mitochondrial Ca2+ efflux. This reaction is accompanied by an increasing energy drain on the system, stimulation of oxygen consumption, and mitochondrial ...
E, Chávez, C, Zazueta, E, Díaz
openaire   +2 more sources

1,3-Dicyclohexylcarbodiimide

2010
[538-75-0] C13H22N2 (MW 206.33) InChI = 1/C13H22N2/c1-3-7-12(8-4-1)14-11-15-13-9-5-2-6-10-13/h12-13H,1-10H2 InChIKey = QOSSAOTZNIDXMA-UHFFFAOYAO (powerful dehydrating agent commonly used for the preparation of amides,2 esters,3 and anhydrides;4 used with DMSO for the mild oxidation of alcohols to ketones;5 used in the ...
Jeffrey S. Albert   +2 more
openaire   +1 more source

Dicyclohexylcarbodiimide-sensitive ATPase in Halobacterium saccharovorum

Archives of Biochemistry and Biophysics, 1985
Membranes from Halobacterium saccharovorum contained a cryptic ATPase which required Mg2+ or Mn2+ and was activated by Triton X-100. The optimal pH for ATP hydrolysis was 9-10. ATP or GTP were hydrolyzed at the same rate while ITP, CTP, and UTP were hydrolyzed at about half that rate. The products of ATP hydrolysis were ADP and phosphate.
H, Kristjansson, L I, Hochstein
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MHC restriction in contact hypersensitivity to dicyclohexylcarbodiimide

Food and Chemical Toxicology, 2002
Mouse ear swelling tests were performed using different strains of mice with dicyclohexylcarbodiimide (DCC), diisopropylcarbodiimide (DIC), di-p-tolylcarbodiimide (DTC), and positive control chemicals, such as dinitrochlorobenzene (DNCB) and oxazolone (OXA).
H, Kato   +3 more
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Light-induced reaction of dicyclohexylcarbodiimide with bacteriorhodopsin

Biochemical and Biophysical Research Communications, 1981
Abstract Bacteriorhodopsin solubilized in Triton X-100 micelles undergoes a light-induced reaction with [14C]-dicyclohexylcarbodiimide at pH 7.5. The reaction has three consequences: 1) incorporation of radioactivity into bacteriorhodopsin, 2) irreversible bleaching of the retinal chromophore, and 3) alteration of the CNBr cleavage pattern.
R, Renthal, N, Dawson, L, Villarreal
openaire   +2 more sources

Stoicheiometry of dicyclohexylcarbodiimide-ATPase interaction in mitochondria

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1982
1. The oligomeric dicyclohexylcarbodiimide (DCCD)-binding protein of mitochondrial ATPase was studied using (a) the relationship between (14C] DCCD binding and inhibition of ATPase activities and (b) the analysis of the kinetics of inhibition. 2. The [14C]DCCD binding to bovine heart mitochondria is linearly proportional to the inhibition of ATP ...
J, Kopecký   +6 more
openaire   +2 more sources

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