Results 61 to 70 of about 127,361 (299)

Myostatin Levels in SMA Following Disease‐Modifying Treatments: A Multi‐Center Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study investigated myostatin levels in SMA patients receiving disease‐modifying therapies (DMTs) to understand their relationship with treatment duration and functional status. Methods Our study includes both cross‐sectional and longitudinal analyses of myostatin levels in treated SMA patients.
Fiorella Piemonte, Sara Petrillo, Anna Capasso, Giorgia Coratti, Adele D'Amico, Michela Catteruccia, Maria Carmela Pera, Concetta Palermo, Marika Pane, Emanuela Abiusi, Gianpaolo Cicala, Marianna Villa, Chiara Bravetti, Chiara Arpaia, Agnese Novelli, Salvatore Falqui, Stefania Fiori, Giulia Napoli, Silvia Baroni, Francesco Danilo Tiziano, Enrico Bertini, Giacomo Comi, Stefania Corti, Eugenio Mercuri   +23 more
wiley   +1 more source

Miniaturized Resonator and Bandpass Filter for Silicon-Based Monolithic Microwave and Millimeter-Wave Integrated Circuits [PDF]

, 2018
© 2018 IEEE. © 2018 IEEE. Personal use is permitted, but republication/redistribution requires IEEE permission.This paper introduces a unique approach for the implementation of a miniaturized on-chip resonator and its application for the first-order ...
Sun, Yichuang, Wong, Sai Wai, Yang, Yang, Zhu, He, Zhu, Xi   +4 more
core   +1 more source

Patient Selection in Deep Brain Stimulation: A Role for Transcranial Direct Current Stimulation to Enhance the Levodopa Challenge?

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Dopaminergic medication and deep brain stimulation (DBS) improve motor symptoms in Parkinson's disease (PD), but levodopa response alone may not predict DBS outcomes. We retrospectively analyzed 19 PD patients undergoing levodopa challenges with and without prior transcranial direct current stimulation targeting a defined PD response network ...
Lukas L. Goede, Patricia Zvarova, Bahne H. Bahners, Andreas Horn   +3 more
wiley   +1 more source

Switched 4-to-1 Transimpedance Combining Amplifier for Receiver Front-End Circuit of Static Unitary Detector-Based LADAR System

Applied Sciences, 2017
Laser detection and ranging (LADAR) systems are commonly used to acquire real-time three-dimensional (3D) images using the time-of-flight of a short laser pulse.
Eun-Gyu Lee, Jae-Eun Lee, Bang Chul Jung, Bongki Mheen, Choul-Young Kim   +4 more
doaj   +1 more source

Simultaneous Bidirectional Signaling for Die-to-Die Links: Signal Integrity Challenges and Hybrid Circuits

IEEE Open Journal of the Solid-State Circuits Society
This article reviews simultaneous bidirectional signaling and its unique signal integrity challenges for die-to-die links: the near-end echo signal and the hybrid circuit required to remove it, signal reflections, and the impact of timing. A few key works in the design of simultaneous bidirectional transceivers are covered, such as dynamic reference ...
Durand Jarrett-Amor, Tony Chan Carusone
openaire   +2 more sources

Stage‐Dependent Inhibitory Connectivity in Striatal‐Motor Circuit in Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Elucidating dysfunctional connectivity patterns among key brain regions in Huntington's disease (HD) underlying progression may have implications for developing treatment and therapeutic evaluation. Objective Explore the relationship between abnormal spontaneous resting‐state activity and atrophy in HD‐specific brain regions and ...
Yinghua Jing, Imis Dogan, Rena Theda Overbeck, Kathrin Reetz, Sandro Romanzetti   +4 more
wiley   +1 more source

A Multi-Channel Low-Power System-on-Chip for in Vivo Recording and Wireless Transmission of Neural Spikes

Journal of Low Power Electronics and Applications, 2012
This paper reports a multi-channel neural spike recording system-on-chip with digital data compression and wireless telemetry. The circuit consists of 16 amplifiers, an analog time-division multiplexer, a single 8 bit analog-to-digital converter, a ...
Alessandro Sottocornola Spinelli, Emma Maggiolini, Marianna Semprini, Alessandro Vato, Gian Nicola Angotzi, Gytis Baranauskas, Riccardo Gusmeroli, Guido Zambra, Maria Ceravolo, Andrea Bonfanti, Andrea Leonardo Lacaita   +10 more
doaj   +1 more source

Application of Silicon Micromachining to Thermal Dissipation Issues in Wafer Scale Integrated Circuits [PDF]

, 1991
The purpose of this research effort was to investigate the feasibility of applying the silicon micromachining technique to thermal management as applied to integrated circuits and wafer scale integration techniques. Three silicon micromachined structures
Cosnyka, Edward
core   +1 more source

Statistical Power Supply Dynamic Noise Prediction in Hierarchical Power Grid and Package Networks [PDF]

, 2008
One of the most crucial high performance systems-on-chip design challenge is to front their power supply noise sufferance due to high frequencies, huge number of functional blocks and technology scaling down.
Casu, Chen, Deutsch, G. Piccinini, Hashemi, Kozhaya, Lee, M. Graziano, Mezhiba, Zhao, Zheng   +10 more
core   +1 more source

A Systematic Clinical Framework for Postimplantation Monitoring in Thalamic Neuromodulation: Insights From Twiddler's Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This case described a 25‐year‐old pregnant woman with refractory multifocal epilepsy, diagnosed in 2020 and treated with bilateral thalamic deep brain stimulation (DBS) targeting the centromedian and pulvinar nuclei. Prior to DBS, she experienced daily focal seizures, often progressing to generalized tonic–clonic seizures despite optimal ...
Shalin Shah, Ganne Chaitanya, Jeston Chin, Nicholas Delcimmuto, Jay R. Gavvala   +4 more
wiley   +1 more source