Parents' Instrumental Family Support, Diet Quality, and Satisfaction with Food-Related Life: A Dyadic Approach in Dual-Earner Parents and Their Adolescent Children. [PDF]
Schnettler B +9 more
europepmc +1 more source
Systematic Multi‐Level Analyses Decode the Arthritis‐Neurodegeneration Axis With In Vivo Validation
Arthritis and neurodegeneration are usually studied as separate disorders, but this study connects them through population evidence, genetic inference, transcriptomic mapping, and mouse models. It highlights RNF40 as a context‐dependent joint‐brain candidate, induced in inflammatory joints yet functionally linked to dopamine‐neuron vulnerability ...
Jinwen Wang +7 more
wiley +1 more source
Behavioral pathways and psychosocial determinants of adolescent mental health: positioning nutrition health literacy as a candidate upstream target. [PDF]
Tuo W, Sicong W, Wei L.
europepmc +1 more source
Toward Personalized Theranostics: A Modular PET Platform for Antibody‐Based Imaging and Therapy
This modular, site‐specific antibody platform enables customizable conjugates for PET imaging and therapy. Interchangeable payloads – including radiometals, cytotoxics, and fluorophores – support adaptable, multimodal applications with limited off‐target effects. In vivo, the DFO/DOTAGA bischelate immunoconjugate provided clear tumor delineation in PET/
Delphine Vivier +16 more
wiley +1 more source
Food Environment Assessment in Two Socioeconomic Contexts in Queensland, Australia. [PDF]
Kadariya S, Parkinson J, Ball L.
europepmc +1 more source
VEGFR‐2 signaling in OSCC activates Src–STAT6‐dependent CSF2 transcription, driving tumor‐derived GM‐CSF secretion. GM‐CSF programs neutrophils to express PD‐L1 through STAT5–mTOR/S6K signaling, suppressing cytotoxic CD8+ T cells. This pathway reveals a tumor–neutrophil immune checkpoint circuit that limits anti‐PD‐1 responsiveness in OSCC.
Fangxing Zhu +13 more
wiley +1 more source
Associations Among Diet Quality, Motor Competence, and Physical Fitness in Preschool Children: A Cross-Sectional Study. [PDF]
de Souza-Lima J +8 more
europepmc +1 more source
A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu +17 more
wiley +1 more source
Legumes: A component of a healthy diet.
Leila Azadbakht +2 more
openaire +2 more sources
Effect of a multicomponent intervention on adherence to the Mediterranean diet in older adults: a randomized controlled trial. [PDF]
Murillo-Zaldívar AM +9 more
europepmc +1 more source

