Results 31 to 40 of about 7,142 (250)

Randomized crossover trial of a modified ketogenic diet in Alzheimer’s disease

Alzheimer’s Research & Therapy, 2021
Background Brain energy metabolism is impaired in Alzheimer’s disease (AD), which may be mitigated by a ketogenic diet. We conducted a randomized crossover trial to determine whether a 12-week modified ketogenic diet improved cognition, daily function ...
Matthew C. L. Phillips, Laura M. Deprez, Grace M. N. Mortimer, Deborah K. J. Murtagh, Stacey McCoy, Ruth Mylchreest, Linda J. Gilbertson, Karen M. Clark, Patricia V. Simpson, Eileen J. McManus, Jee-Eun Oh, Satish Yadavaraj, Vanessa M. King, Avinesh Pillai, Beatriz Romero-Ferrando, Martijn Brinkhuis, Bronwyn M. Copeland, Shah Samad, Shenyang Liao, Jan A. C. Schepel   +19 more
doaj   +1 more source

ADCY3: the pivotal gene in classical ketogenic diet for the treatment of epilepsy

Frontiers in Cellular Neuroscience
ObjectiveEpilepsy is a common neurological disorder characterized by recurrent epilepsy episodes. As a non-pharmacological treatment, the ketogenic diet has been widely applied in treating epilepsy.
Mingxing Lin, Jiayin Gong, Luyan Wu, Xin Lin, Yuying Zhang, Wanhui Lin, Huapin Huang, Huapin Huang, Huapin Huang, Chaofeng Zhu   +9 more
doaj   +1 more source

Myeloid p38 activation maintains macrophage–liver crosstalk and BAT thermogenesis through IL‐12–FGF21 axis

Hepatology, EarlyView., 2022
Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo, Ivana Nikolic, Alfonso Mora, Elena Rodríguez, Luis Leiva‐Vega, Aránzazu Pintor‐Chocano, Daniel Horrillo, Lourdes Hernández‐Cosido, Jorge L. Torres, Eva Novoa, Rubén Nogueiras, Gema Medina‐Gómez, Miguel Marcos, Magdalena Leiva, Guadalupe Sabio   +14 more
wiley   +1 more source

The impact of the ketogenic diet on the health of patients with Alzheimer’s disease

Journal of Education, Health and Sport
INTRODUCTION: Diet is an integral element of every individual's health. Its impact on the functioning of the human body has fascinated scientists for years.
Julia Samborska, Paweł Więckowiak, Karina Stelmaszak, Katarzyna Stencel, Aleksandra Ogiegło-Kowalczyk, Monika Wojtasik, Michał Głodzik, Marek Miśkiewicz, Katarzyna Żak, Martyna Łęcka   +9 more
doaj   +1 more source

The effects of moderate-intensity continuous training and high-intensity interval training during a ketogenic diet on serum levels of irisin, PGC-1α and UCP1 in overweight and obese women [PDF]

فیزیولوژی ورزش و فعالیت بدنی
Background and Purpose: Nowadays, obesity has become a global challenge, and the use of strategies based on diet and exercise is recommended by experts and researchers for weight management.
Behnam Behravan, Kazem Khodaei, Mohammadreza Zolfaghardidani   +2 more
doaj   +1 more source

Ketogenic diets

Indian Journal of Medical Research, 2018
Ketogenic diets are characterized by a marked reduction in carbohydrates (usually to
Shilpa, Joshi, Mohan, Viswanathan
openaire   +2 more sources

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Experience with the ketogenic diet in premature neonates

Epilepsia Open, 2023
The ketogenic diet is a time‐tested, potent, nonpharmacological treatment of epilepsy. However, the use of the ketogenic diet in premature neonates with epilepsy has not been previously reported.
Chalongchai Phitsanuwong, Jeong‐A Kim, Stephanie Schimpf, Douglas R. Nordli Jr   +3 more
doaj   +1 more source

Ketogenic diet in pediatric epilepsies

, 2023
Epilepsy is a disorder of the brain characterized by an enduring predisposition to generate epileptic seizures, and by several neurobiological, cognitive, psychological, and social consequences. The incidence of epilepsy in pediatric age ranges from 41
SABRINA DE LEO, FEDERICA GIGLIOTTI, MARIO MASTRANGELO, DARIO ESPOSITO   +3 more
core   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source