Results 291 to 300 of about 4,549,733 (400)

CRISPR‐MI and scRNA‐Seq Reveal TREM2's Function in Monocyte Infiltration and Macrophage Apoptosis During Abdominal Aortic Aneurysm Development

Advanced Science, EarlyView.
A method is developed for conducting genome‐wide CRISPR/Cas9 screening of monocyte infiltration in vivo (CRISPR‐MI) that is easily adaptable across a variety of disease models. Through the combination of CRISPR‐MI and scRNA‐Seq, this study discovers that Trem2 is a key regulator of early monocyte infiltration in abdominal aortic aneurysm (AAA ...
Haocheng Lu, Chao Xue, Yang Zhao, Jinjian Sun, Changzhi Zhao, Xu Zhang, Guizhen Zhao, Yaozhong Liu, Hongyu Liu, Yongjie Deng, Ying Wang, Chi Zhang, Yingjie Liu, Linjun Zeng, Ying Yang, Bolun Li, Shusi Ding, Linkang Zhou, Henry Kuang, Zanxin Wang, Wenhao Ju, Haihuan Lin, Jie Lin, Yanhong Guo, Lin Chang, Hongmei Zhao, Jing Wang, Jiandie Lin, Lemin Zheng, Y. Eugene Chen, Jifeng Zhang   +30 more
wiley   +1 more source

Pathways Contributing to Chemotherapy-Induced Myotoxicity Are Attenuated by EPA + DHA in a Clinically Relevant Model of Colorectal Cancer. [PDF]

J Cachexia Sarcopenia Muscle
Isesele PO, Bhatt BJ, Baracos VE, Damaraju S, Mazurak VC.   +4 more
europepmc   +1 more source

Western diet consumption impairs memory function via dysregulated hippocampus acetylcholine signaling

Anna Hayes, Logan Tierno Lauer, Alicia E. Kao, Shan Sun, Molly E. Klug, Linda Tsan, Jessica J. Rea, Keshav S. Subramanian, Cindy Gu, Natalie Tanios, Arun Ahuja, Kristen N. Donohue, Léa Décarie-Spain, Anthony A. Fodor, Scott E. Kanoski   +14 more
openalex   +2 more sources

Does social class predict diet quality?

American Journal of Clinical Nutrition, 2008
N. Darmon, A. Drewnowski
semanticscholar   +1 more source

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

Advanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian, Jing Zhu, Jianhong Wu, Yan Zhang, Jianghua Chen, Huan Wang, Hengyan Liu, Ke Xu, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Shilin Li, Tingting Wang, Xuan Huang, Qinghua Zou, Jie Zhang, Jiang Su, Xinming Du, Yaping Lu, Tianci Zhou, Yingtong Zhou, Minglong Tang, Bin Li, Xue Zhou, Qihao Wei, Qiulong Yan, Fanxin Zeng   +26 more
wiley   +1 more source

The benefit of diet on paradoxical breathing and sleep in Osteogenesis imperfecta. [PDF]

Orphanet J Rare Dis
LoMauro A, De Amicis R.
europepmc   +1 more source

Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery.

New England Journal of Medicine, 2002
D. Cummings, D. Weigle, R. S. Frayo, P. Breen, Marina K. Ma, E. Dellinger, J. Purnell   +6 more
semanticscholar   +1 more source

FBXO44 Regulates FOXP1 Degradation Through AURKA‐Dependent Phosphorylation to Promote Colorectal Cancer Progression

Advanced Science, EarlyView.
FBXO44 promotes colorectal cancer progression by targeting FOXP1 for ubiquitin‐mediated degradation. This study reveals a phosphorylation‐dependent mechanism involving AURKA and highlights the FBXO44/FOXP1/Cyclin E2 axis as a potential therapeutic target in colorectal cancer.
Hongxu Nie, Hengjie Xu, Sheng Yang, Chuanxin Tian, Tuo Wang, Chi Jin, Zhihao Chen, Xiaowei Wang, Junwei Tang, Yifei Feng, Yueming Sun   +10 more
wiley   +1 more source

Impact of low-FODMAP diet on symptom relief in irritable bowel syndrome patients. [PDF]

Asia Pac J Clin Nutr
Luo Y, Xu Z, Li R, Zhang Q, Wu Z.
europepmc   +1 more source

Origins and evolution of the Western diet: health implications for the 21st century.

American Journal of Clinical Nutrition, 2005
L. Cordain, S. Eaton, A. Sebastian, N. Mann, S. Lindeberg, B. Watkins, J. O’Keefe, J. Brand-Miller   +7 more
semanticscholar   +1 more source