Results 301 to 310 of about 4,611,077 (397)

Icaritin Ameliorates Cisplatin‐Induced Mitochondrial Metabolic Dysfunction‐Associated Nephrotoxicity and Synergistically Potentiates Its Antitumor Efficacy

Advanced Science, EarlyView.
In this study, scRNA‐seq and chemoproteomics are integrated to characterize CDDP‐bound proteins at single‐cell resolution in tumor‐bearing mice. Additionally, the research demonstrates that ICA alleviates CDDP‐induced nephrotoxicity while enhancing its chemotherapeutic efficacy.
Piao Luo, Junhui Chen, Yehai An, Kun Meng, Wei Zhou, Wenhui Li, Jing Liu, Wentong Zhao, Weiyi He, Ting Cao, Jingnan Huang, Sha Feng, Shiguang Yang, Hongling Hu, Jiaxian Liao, Hengkai He, Mingjing Hao, Qian Zhang, Jigang Wang, Yue Gao   +19 more
wiley   +1 more source

Mitigating heat stress impact on laying quails: antioxidant effects of grape seed and black mulberry leaf powder on growth, egg quality, and biochemical parameters. [PDF]

Trop Anim Health Prod
Sur A, Zengin M, Bacaksiz OK, Demir E, Esen S.   +4 more
europepmc   +1 more source

Methionine-Cystine Interrelationships in Chicks and Rats Fed Diets Containing Suboptimal Levels of Methionine

, 1980
David R. Sell, W.R. Featherston, J.C. Rogler   +2 more
openalex   +1 more source

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

Advanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren, Renhe Cao, Xiaoshan Ye, Wenbin Pang, Qingshang Bi, Meihui Huang, Qionglin Zhou, Dan Ye, Wei Xiang, Le Xiao   +9 more
wiley   +1 more source

Hyperfiltration and Metabolism Before and After a Low-Calorie, Pre-Gastric Bypass Surgery Diet: Significance for Concentrations of Hydrophilic and Lipophilic Drugs. [PDF]

Basic Clin Pharmacol Toxicol
Axelsson MAB, Wallerstedt SM.
europepmc   +1 more source

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

Advanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li, Chenyang Meng, Guangcong Shen, Yueying Shan, Junjin Wang, Diliyaer Abudukeremu, Rui Zhao, Bo Ni, Chao Xu, Xiaofan Guo, Jun Yu, Kaiyuan Wang, Shengyu Yang, YunZhan Li, Yongjie Xie, Tianxing Zhou, Jihui Hao, Xiuchao Wang   +17 more
wiley   +1 more source

Diet-Related Health Recommender Systems for Patients With Chronic Health Conditions: Scoping Review.

J Med Internet Res
Dong X, Yun B, Pakarinen A, Zheng Z, Niu H, Jin T, Yuan C, Wang J.   +7 more
europepmc   +1 more source

Dietary medium chain triglycerides impairs orexigenic action of ghrelin in mice. [PDF]

Front Endocrinol (Lausanne)
Aotani D, Ariyasu H, Tanaka T, Shimazu-Kuwahara S, Nomura H, Shimizu Y, Takeda K, Koyama H, Kusakabe T, Miyazawa T, Hikida T, Kataoka H, Nakao K.   +12 more
europepmc   +1 more source