Results 301 to 310 of about 4,549,733 (400)

Pre‐Administration of Akkermansia Muciniphila Prevents the Development of Severe Acute Graft‐Versus‐Host Disease in Systemic Organs

Advanced Science, EarlyView.
Akkermansia muciniphila, a next‐generation probiotic, alleviates acute graft‐versus‐host disease (aGvHD) following allogeneic hematopoietic stem cell transplantation (HSCT) by providing protective effects across multiple organs. Pre‐colonization with A.
Jeong‐Eun Han, Dae‐Seong Lee, Su‐Won Jeong, Ji‐Hyun Yun, Seomin Kang, Seoyoung Jang, EunAh Lee, Ju Hye Baek, Che Ok Jeon, Jin‐Woo Bae   +9 more
wiley   +1 more source

Eating within planetary boundaries - a cross-country analysis of iodine provision from the EAT-Lancet diet. [PDF]

NPJ Sci Food
Nicol K, Nugent AP, Woodside JV, Hart KH, Lynch K, Mangan N, Bath SC.   +6 more
europepmc   +1 more source

Obesity‐Associated TRIM15 Promotes the Proliferation of Esophageal Adenocarcinoma Through the YY2/FOXRED1 Axis

Advanced Science, EarlyView.
The study identifies TRIM15 as a key driver in the development of obesity‐associated esophageal adenocarcinoma (EAC). Mechanistically, TRIM15 degrades YY2 through the proteasome pathway, suppressing FOXRED1 transcription and ultimately accelerating tumor proliferation.
Haohui Wang, Chong Yang, Dayuan Luo, Pingting Liu, Zhen Zeng, Weilin Peng, Dongzi Peng, Hao Su, Xiaoxiong Xiao, Haiqin Wang, Xin Jin   +10 more
wiley   +1 more source

Metabolic signature of EAT-Lancet diet in relation to risk of frailty: a prospective cohort study. [PDF]

NPJ Sci Food
Guo J, Kou G, Zhu Y, Liang R, Ye H, Suo X, Bo Y.   +6 more
europepmc   +1 more source

A negative feedback loop between microRNA-378 and Nrf1 promotes the development of hepatosteatosis in mice treated with a high fat diet

, 2018
Tianpeng Zhang, Xiaoling Zhao, Clifford J. Steer, Guiqin Yan, Guisheng Song   +4 more
openalex   +1 more source

RELA Ablation Contributes to Progression of Hepatocellular Carcinoma with TP53R249S Mutation and is a Potential Therapeutic Target

Advanced Science, EarlyView.
Genome‐wide CRISPR/Cas9 based screening identified RELA as a key tumor suppressor in TP53R249S‐mutant HCC. Its loss promotes tumorigenesis and metastasis via DVL1‐mediated Wnt/β‐catenin activation, while its agonist betulinic acid suppresses tumor progression.
Zhiping Wu, Zhe Wang, Diwei Zheng, Yongfang Zheng, Zhiwu Jiang, Jiang Lv, Yueqin Zhu, Heng Jia, Ziyuan Duan, Tingjie Yuan, Qiting Wu, Youguo Long, Shouheng Lin, Yao Yao, Georgia Carson, Jean P. Thiery, Kwan Man, Peng Li   +17 more
wiley   +1 more source

Nutritional modulation of host physiology, behavior, and gut microbiome in the captive rodent Octodon degus. [PDF]

Sci Rep
Rivera DS, Beltrán V, Hoepfner C, Del Pilar Fernández M, Oliva CA, Vera MJ, Farías C, Valenzuela R, Pérez I, Correa LA, Urbina F.   +10 more
europepmc   +1 more source

Antimicrobial and cytotoxic activities of the crude extracts of Dietes bicolor leaves, flowers and rhizomes

, 2014
Iriny M. Ayoub, Mohamed El‐Shazly, Mei‐Chin Lu, Abdel Nasser B. Singab   +3 more
openalex   +1 more source

The Pathogenic Roles of Local Vitamin D Metabolism Defect in Valve Inflammation and Calcification

Advanced Science, EarlyView.
This study identifies the valvular interstitial cell populations responsible for valvular calcification induced by hyperphosphatemia and likely aging, uncovers local vitamin D metabolism defect‐induced inflammation as a critical pathogenic factor of calcific aortic valve disease, and highlights active vitamin D and ERK inhibitor as potential preventive
Ruichen Yang, Chong Han, Yangli Xie, Shoutao Qiu, Shaoyang Zhang, Jingjia He, Zejian Wang, Zhenlin Zhang, Huijuan Liu, Lin Chen, Baojie Li   +10 more
wiley   +1 more source

Linking Personality Traits to Mediterranean Diet Adherence and Exploring Gene-Diet Interactions in Neuroticism. [PDF]

Nutrients
Sorlí JV, Ortega-Azorín C, Coltell O, Fernández-Carrión R, Asensio EM, Portolés O, Perez-Fidalgo A, Ramirez-Sabio JB, Guillem-Saiz J, Costa JA, Gimenez-Alba IM, Barragán R, Ordovas JM, Corella D.   +13 more
europepmc   +1 more source