Results 371 to 380 of about 4,225,955 (410)

SSRP1/SLC3A2 Axis in Arginine Transport: A New Target for Overcoming Immune Evasion and Tumor Progression in Peripheral T‐Cell Lymphoma

Advanced Science, EarlyView.
Enhanced arginine uptake is a critical feature of metabolic reprogramming in PTCL, characterized by elevated expression of the arginine transporter SLC3A2. SLC3A2‐mediated arginine uptake facilitates PTCL proliferation and survival by enhancing OXPHOS metabolism and inducing immune evasion.
Yimin Ren, Lei Fan, Ling Wang, Yanping Liu, Jie Zhang, Boya Wang, Ruize Chen, Xiao Chen, Lingyu Zhuang, Yaping Zhang, Handong Sun, Jianyong Li, Wenyu Shi, Hui Jin   +13 more
wiley   +1 more source

Mediterranean diet and prime diet quality score are associated with reduced risk of premature coronary artery disease in Iran: a multi-centric case-control study. [PDF]

Sci Rep
Mohammadifard N, Rahimlou M, Amani-Beni R, Darouei B, Zarepur E, Haghighatdoost F, Nazemzadeh-Harandi S, Azdaki N, Salehi N, Lotfizadeh M, Ghaffari S, Salari A, Dehghani M, Assareh A, Sarrafzadegan N.   +14 more
europepmc   +1 more source

Asprosin‐FABP5 Interaction Modulates Mitochondrial Fatty Acid Oxidation through PPARα Contributing to MASLD Development

Advanced Science, EarlyView.
Aided by FABP5, abnormally elevated asprosin in hepatocytes enters the nucleus, targets and inhibits PPARα binding to the CPT1A promoter, thereby suppressing FAO. Circulating asprosin exacerbates insulin resistance, collectively driving MASLD progression.
Yuan‐Yuan Yu, Min Feng, Yi Chen, Hong‐Lin Jia, Qi Zhang, Ming Tong, Yan‐Xi Li, Yu Zhao, Xin‐Xin Liu, Shi‐Feng Cao, Zheng‐kai Wang, Hou‐wei Li, Xue Liu, Yan Zhang   +13 more
wiley   +1 more source

Impact of Diets on Cognitive and Clinical Outcomes in Alzheimer's Disease: A Scoping Review. [PDF]

Cureus
Jackson Q, Fricker R, Toska E, Ottley A, Carleo A, Cutrali G, D'Alessio O, Rossman R, Kruchakov S, Edelstein A, Nathanson L.   +10 more
europepmc   +1 more source

Mechanisms of Baicalin Alleviates Intestinal Inflammation: Role of M1 Macrophage Polarization and Lactobacillus amylovorus

Advanced Science, EarlyView.
Baicalin alleviates E. coli‐induced intestinal inflammation through dual mechanisms: direct inhibition of the TLR4/IRF/STAT signaling pathway to modulate macrophage polarization and antigen presentation, thereby regulating Th17/Treg cell differentiation; and microbiota‐mediated indirect effects via increasing Lactobacillus amylovorus abundance and ...
Shunfen Zhang, Ruqing Zhong, Miao Zhou, Kai Li, Huiyuan Lv, Huixin Wang, Ye Xu, Dadan Liu, Qiugang Ma, Liang Chen, Hongfu Zhang   +10 more
wiley   +1 more source

Sex-Specific Effect of a High-Energy Diet on Body Composition, Gut Microbiota, and Inflammatory Markers in Rats. [PDF]

Nutrients
Minaya DM, Hoss A, Bhagat A, Guo TL, Czaja K.   +4 more
europepmc   +1 more source

IRF8 Drives Conventional Type 1 Dendritic Cell Differentiation and CD8+ T Cell Activation to Aggravate Abdominal Aortic Aneurysm Development

Advanced Science, EarlyView.
This study highlights the critical role of IRF8 in the development of AAA. IRF8 activation promotes the differentiation of cDC1s, which in turn recruit and activate CD8+ T cells, contributing to aortic wall degradation. The study identifies the IRF8‐cDC1‐CD8+ T cell axis as a key pathway in AAA progression, offering new potential therapeutic targets to
Zhen Yuan, Li Shu, Yidan Zheng, Yidong Wang, Mengsha Zheng, Jie Sun, Jiantao Fu, Zihao Zhou, Shen Song, Zhenjie Liu, Fei Li, Zhejun Cai   +11 more
wiley   +1 more source

Comparison of absorption and excretion of test compounds in sucking versus chewing pests. [PDF]

PLoS One
Römer CI, Ashauer R, Escher BI, Hollender J, Burkhard R, Höfer K, Muehlebach M, Buchholz A.   +7 more
europepmc   +1 more source

Standard mouse diets lead to differences in severity in infectious and non-infectious colitis. [PDF]

mBio
Denny JE, Flores JN, Mdluli NV, Abt MC.
europepmc   +1 more source

Effects of supplemental hybrid bacterial 6-phytase in low-energy, inorganic phosphorus-free hen diets on laying performance, egg quality, and bone strength. [PDF]

PLoS One
Sacakli P, Ramay MS, Ceylan A, Çınar ÖÖ, Elibol FKE, Harijaona JA, Shastak Y, Ader P, Feuerstein D, Calik A.   +9 more
europepmc   +1 more source