Results 131 to 140 of about 7,818,453 (260)

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

Advanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu, Miaozhan Zou, Yunshang Bai, Yang He, Zhihao Jin, Baozhi Yang, Jinjin Du, Pei Ouyang, Yuanyuan Cai, Yuheng Zhang, Bingying Du, Chengcheng Ge, Jian‐an Gong, Xiaoyu Li, Yuanyi Zheng, Jing Ding, Bo Peng, Yanxia Rao   +17 more
wiley   +1 more source

Diet quality in Kazakhstan schools and kindergartens: Implications for national nutrition policy. [PDF]

J Educ Health Promot
Tardjibayeva SK, Abduldayeva AA, Doszhanova GN, Safonov NA, Mukhanbetova NA, Iskakova SA.   +5 more
europepmc   +1 more source

TRAIP Mediates Alcohol‐Induced Liver Injury through Regulating β‐catenin Ubiquitin Degradation via Direct Interaction

Advanced Science, EarlyView.
This study reveals that NF‐κB1‐driven TRAIP upregulation in ALD correlates with disease severity. Mechanistically, TRAIP directly binds β‐catenin via its CC domain and promotes its K48‐linked ubiquitination and degradation, which is independent of the GSK3β/β‐TrCP pathway.
Zhan Wu, Mingjiang Liu, Lijuan Liao, Zhaohong Mo, Wenli Xu, Linfeng Mao, Yubing Chen, Qiuli Xie, Ming Yao, Shilian Chen, Stephen Tomlinson, Sebastian Mueller, Songqing He, Guandou Yuan   +13 more
wiley   +1 more source

Associations between diet quality, epigenetic aging and epigenome in two population-based cohorts. [PDF]

Nat Commun
Tavares JF, Liu D, Talevi V, Eichelmann F, Jannasch F, Schulze MB, Aziz NA, Nöthlings U, Breteler MMB.   +8 more
europepmc   +1 more source

Charting Endocrine Progenitors Across Species and Organs

Advanced Science, EarlyView.
Endocrine progenitors give rise to the hormone‐producing cells of the pancreas and intestine. Using single‐cell multiomics and proteomics, this study compares these progenitors across species, systems, and organs, mapping the conserved and species‐specific gene regulatory networks that guide their formation.
Changying Jing, Michael Sterr, Özüm Sehnaz Caliskan, Lama Saber, Nicole Katarina Rogers, Samuel Ogden, Kei Kozawa, Christos Karampelias, Jessica Jaki, Aimée Bastidas‐Ponce, Falk Janos Farkas, Oliver Czarnecki, Osvaldo Rodrigues Pereira, Perla Cota, Valerie Vandenbempt, Diego Balboa, Anika Böttcher, Natalie Krahmer, Mohammad Lotfollahi, Julie B. Sneddon, Heiko Lickert, Mostafa Bakhti   +21 more
wiley   +1 more source

Lower Health Literacy Is Associated with Poorer Diet Quality in Korean Adults: An Association Masked by Age. [PDF]

Nutrients
Joo H, Choi J.
europepmc   +1 more source

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

Advanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo, Caian He, Xiao Xiao, Jingmeng Li, Zilong Zhang, Ying He, Chuanchuan Wang, Jiale Zhao, Jun Gong, Jiarui Liang, Tian Yuan, Haiting Sun, Xuebo Liu, Chao Gao, Zhigang Liu   +14 more
wiley   +1 more source

Safeguarding diet quality in a changing climate: a scoping review. [PDF]

Front Nutr
Mutonhodza B, Ndemera M, Govender L, Reuzé A, Ngidi MSC, Siwela M, Mabhaudhi T.   +6 more
europepmc   +1 more source

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

Advanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu, Chong Wu, Shiyao Song, Li Ma, Shaoqing Huang, Yuting He, Qinghai Li, Yanzhou Chang, Dan Jiang, Yong Mei, Junchao Cai, Zhenshuang Du, Tianfeng Chen, Weiling He   +13 more
wiley   +1 more source

The 'Diet Quality Index' and its applications

, 2013
B
Vereecken, CarineUGent001987004984801001008352975579911963F4E39548-F0ED-11E1-A9DE-61C894A0A6B4, De Henauw, StefaanGE398010007602930000-0003-4141-5432F47B132E-F0ED-11E1-A9DE-61C894A0A6B4, Preedy, Victor Reditor, Maes, LeaUGent8010003445109758639919240000-0003-2909-6010F3C1BFC8-F0ED-11E1-A9DE-61C894A0A6B4, Huybrechts, IngeUGent0019932766428010017133219797029140400000-0003-3838-855XFA0E1570-F0ED-11E1-A9DE-61C894A0A6B4, Hunter, Lan-Anheditor, Patel, Vinood Beditor, Vyncke, KrishnaUZGent00200246415880200061821087011089228102EE263A-F0EE-11E1-A9DE-61C894A0A6B4, Slimani, Nadia   +8 more
core