Results 61 to 70 of about 519,796 (305)
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Background and Objectives: Depression is one of the fourth most common diseases and will be the second most prevalent disease in the world by 2020 predicted by the World Health Organization. Considering the high frequency of depression among students and
Mohammad Hozoori +5 more
doaj
Supplementing exogenous enzymes in pig diets is an alternative solution to increase dietary energy and fiber digestibility to improve pig production performance at a low production cost and to reduce environmental impact with lower N and P excretions ...
Edgar Aranda-Aguirre +4 more
doaj +1 more source
An ontology to standardize research output of nutritional epidemiology : from paper-based standards to linked content [PDF]
Background: The use of linked data in the Semantic Web is a promising approach to add value to nutrition research. An ontology, which defines the logical relationships between well-defined taxonomic terms, enables linking and harmonizing research output.
Ambayo, Henry +9 more
core +1 more source
Accuracy of weighed dietary records in studies of diet and health. [PDF]
To provide an independent evaluation of seven day weighed dietary records, which are currently accepted as the most accurate technique for assessing habitual dietary intake in studies investigating the links between diet and health.Subjects who had previously participated in the Northern Ireland diet and health study were reselected by stratified ...
M B, Livingstone +7 more
openaire +2 more sources
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu +11 more
wiley +1 more source
Repeatability and validity of a food frequency questionnaire in free-living older people in relation to cognitive function [PDF]
Objectives: To determine the repeatability and validity of a self-administered, 175-item food frequency questionnaire (FFQ) in free-living older people and to assess whether these are influenced by cognitive function.
Aucott, Lorna S +4 more
core
Ecological research is often hampered by the inability to quantify animal diets. Diet composition can be tracked through DNA metabarcoding of faecal samples, but whether (complex) diets can be quantitatively determined with metabarcoding is still debated and needs validation using free-living animals.
Yvonne Verkuil +8 more
openaire +1 more source
ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick +14 more
wiley +1 more source

