Results 91 to 100 of about 362,449 (298)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Influence of dietary calcium intake on quantitative and qualitative parameters of bone tissue in Polish adults

Annals of Agricultural and Environmental Medicine, 2016
Introduction The objective of the study was to assess dietary calcium intake in the Polish population and its influence on selected parameters of bone tissue.
Elżbieta Skowrońska-Jóźwiak, Maciej Jaworski, Roman Lorenc, Andrzej Lewiński   +3 more
doaj   +1 more source

Dietary Acid Load and Bone Turnover During Long-Duration Spaceflight and Bed Rest [PDF]

Background Bed rest studies document that a lower dietary acid load is associated with lower bone resorption. Objective We tested the effect of dietary acid load on bone metabolism during spaceflight. Design Controlled 4-d diets with a high or low animal
Dlouhy, Holly, Heer, Martina, Koslovsky, Matthew, Rice, Barbara L., Shackelford, Linda C., Smith, Scott M., Zwart, Sara R.   +6 more
core   +1 more source

Elevated dietary magnesium during pregnancy and postnatal life prevents ectopic mineralization in Enpp1asj mice, a model for generalized arterial calcification of infancy. [PDF]

, 2017
Generalized arterial calcification of infancy (GACI) is an autosomal recessive disorder caused by mutations in the ENPP1 gene. It is characterized by mineralization of the arterial blood vessels, often diagnosed prenatally, and associated with death in ...
Kingman, Joshua, Li, Qiaoli, Uitto, Jouni   +2 more
core   +1 more source

Vitamin D Status and Bone Mineral Density in Female Collegiate Dancers and Cheerleaders [PDF]

, 2017
Bone mineral density reflects an athlete’s cumulative history of energy availability, physical activity, and menstrual status, as well as nutritional and environmental factors.
Kenny, Tara Sue, Kruskall, Laura J., McCune, Damon, Navalta, James, Young, John C.   +4 more
core   +2 more sources

Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane, Anna Capasso, Chiara Arpaia, Adele D’Amico, Emilio Albamonte, Federica Trucco, Maria Sframeli, Riccardo Masson, Francesca Magri, Luca Bello, Romina Venditti, Claudia Dosi, Michela Catteruccia, Michele Tosi, Claudio Bruno, Sonia Messina, Giacomo Comi, Elena Pegoraro, Valeria A. Sansone, Eugenio Mercuri   +19 more
wiley   +1 more source

Non pharmachological control of plasma cholesterol [PDF]

, 2009
paper di riferimento italiano, basato sui dati scientifici EBM - da capire e approfondire e ricordare e applicare nella pratica ...
Gaddi, Antonio Vittorino
core  

Circulating 250HD, dietary vitamin D, PTH, and calcium associations with incident cardiovascular disease and mortality: The MIDSPAN Family Study [PDF]

, 2012
<p>Context: Observational studies relating circulating 25-hydroxyvitamin D (25OHD) and dietary vitamin D intake to cardiovascular disease (CVD) have reported conflicting results.</p> <p>Objective: Our objective was to investigate the ...
Abu-Rmeileh, Alex McConnachie, Anagnostis, Antonia Hardcastle, Bjelakovic, Bolland, Carole Hart, Carstairs, de Borst, Devereux, Dobnig, Emma Boulton, Food Standards Agency, Forrest, Geraldine McNeil, Giovannucci, Graham Watt, Grandi, Great Britain Committee on Medical Aspects of Food Policy Working Group on the Nutritional Status of the Population of Great Britain Department of Health, Hart, Helen Macdonald, Information Services Division, Jassal, Jia, Knox, Knox, Logue, Macdonald, Mark Upton, Marniemi, Melamed, Michaëlsson, Michos, Naveed Sattar, Orla Doolin, Paul Welsh, Reis, Rhein, Ross, Sattar, Sattar, Scottish Intercollegiate Guidelines Network, Semba, Talwar, Todd, Upton, Wang Wang, Williams, Yarnell, Zittermann   +49 more
core   +1 more source

Calcium intake: good for the bones but bad for the heart? An analysis of clinical studies

Archives of Endocrinology and Metabolism
The proper dietary calcium intake and calcium supplementation, when indicated, are important factors in the acquisition of peak bone mass during youth and in the prevention of fractures in old age.
Guilherme Alcantara Cunha Lima, Priscilla Damião Araújo Lima, Maria da Glória Costa Reis Monteiro de Barros, Lívia Paiva Vardiero, Elisa Fernandes de Melo, Francisco de Paula Paranhos-Neto, Miguel Madeira, Maria Lucia Fleiuss de Farias   +7 more
doaj   +1 more source

Nutritional Contributions of Nonalcoholic Beverages to the U.S. Diet: 1998-2003 [PDF]

Using data from U.S. households over the period 1998 to 2003, we examine economic and demographic factors affecting per capita daily intake of calories, calcium, caffeine, and vitamin C derived from the consumption of nonalcoholic beverages.
Capps, Oral, Jr., Clauson, Annette L., Dharmasena, Senarath   +2 more
core   +1 more source