Microbial Biosensor for Sensing and Treatment of Intestinal Inflammation
The engineered calprotectin biosensor detects gut inflammation, processes the signal through genetic regulation, and responds by expressing the reporter sfGFP and the therapeutic protein secIL10. This dual functionality enables the engineered biosensor not only to sense but also to mitigate gut inflammation, highlighting its potential for disease ...
Duolong Zhu+8 more
wiley +1 more source
Low dietary calcium intake leads to a higher colorectal cancer burden in countries with low social development: findings from the Global Burden of Disease Study 2021. [PDF]
Wu J+8 more
europepmc +1 more source
Dietary calcium intake was related to the onset of pre-eclampsia: The TMM BirThree Cohort Study. [PDF]
Ohseto H+13 more
europepmc +1 more source
This study investigates the critical mechanisms underlying pulmonary hypertension progression, with a focus on the novel role of neutrophil‐derived S100A9 in endothelial dysfunction‐mediated pulmonary vascular remodeling. By integrating human lung samples, multi‐omics analyses, animal models, and mechanistic in vitro studies, it is revealed that how ...
Yu Guo+13 more
wiley +1 more source
Intestinal Clock Promotes Cognitive Memory Through Adenosine Signaling
The intestinal clock controls the expression of an adenosine enzyme that modulates systemic adenosine level and A1R signaling in the hippocampus, and in turn, cognitive function involving long‐term potentiation and BDNF‐dependent synaptic changes.
Min Chen+13 more
wiley +1 more source
Determination of optimal dietary calcium levels under different zinc sources in Jing Tint 6 layer chicks from hatch to day 14. [PDF]
Gong C+7 more
europepmc +1 more source
Indole‐3‐acetic acid (3‐IAA) derived from gut P. distasonis binds to AhR in bladder cancer cells and downregulates FASN transcription, thereby increasing sensitivity to ferroptosis and suppressing the development of bladder tumors. Specifically, 3‐IAA treatment leads to an increase in the proportion of PC/PE‐PUFAs and a decrease in the proportions of ...
Weijia Li+16 more
wiley +1 more source
Dietary calcium and non-phytate phosphorus levels affect performance, follicular development, and egg quality of native chicken at peak laying period. [PDF]
Cheng LF+8 more
europepmc +1 more source
Specific Gravity of Eggs as Influenced by Dietary Calcium and time of oviposition
D.A. Roland, B.L. Damron, R.H. Harms
openalex +1 more source