Results 191 to 200 of about 1,555,355 (288)

The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy

open access: yesAdvanced Science, EarlyView.
Hyperuricemia induces NLRP3 inflammasome signaling activation and downregulation of GPX3 in proximal tubular epithelial cells, leading to oxidative stress–driven VCAM1 upregulation, emergence of pro‐fibrotic proximal tubule cells, macrophage recruitment, and renal fibrosis.
Yunfei Qi   +11 more
wiley   +1 more source

Beyond Conventional: A Review of Phytochemical‐Hydrogel Systems Enhanced by AI and 3D Printing for Chronic Wound Management

open access: yesAdvanced Science, EarlyView.
This review systematically bridges chronic wound pathology with natural phytochemical hydrogel therapeutics. A pathology‐to‐phytochemical mechanistic mapping framework is established, linking specific wound hallmarks to targeted phytochemical interventions.
Yitao Zhou   +8 more
wiley   +1 more source

Heavy Metal Contamination: Impacts From Plants to the Food Chain and Eco‐Friendly Amelioration Strategies

open access: yesAgriFood: Journal of Agricultural Products for Food, EarlyView.
Heavy metal pollution reduces soil health and threatens food safety by entering plants; however, the use of nanoparticles, biofertilizers, and organic fertilizers such as biochar offers a promising strategy for improvement and sustainable agriculture. ABSTRACT Heavy metal (HM) pollution, resulting from human activities such as mining and the excessive ...
Sina Siavash Moghaddam   +4 more
wiley   +1 more source

Improving the Physicochemical Properties, Organic Acids, Amino Acids, Volatile Organic Compounds, and Metabolites of Laohan Melon Juice Through Fermentation With Different Lactic Acid Bacteria

open access: yesAgriFood: Journal of Agricultural Products for Food, EarlyView.
Fermentation with lactic acid bacteria could improve amino acids, volatile organic compounds (VOCs), and nonvolatile metabolites of Laohan melon juice (LMJ), which provides theoretical guidance for the development of Laohan melon beverage and advances knowledge of the metabolic mechanisms of VOCs in LMJ.
Yun Xie   +12 more
wiley   +1 more source

Valorizing Food Waste (Banana Peel) Into an Edible Product: A Study on the Effect of Banana Peel Flour on the Physicochemical, Antioxidant, Textural, and Sensory Properties of Cookies

open access: yesAgriFood: Journal of Agricultural Products for Food, EarlyView.
This study investigated the impact of banana peel flour (BPF) incorporation on cookies' nutritional, functional, physical, and antioxidant properties. The inclusion of BPF led to significant changes in the moisture, protein, crude fat, and ash contents of the developed cookies.
Km. Gudiya   +3 more
wiley   +1 more source

Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities

open access: yesAGING MEDICINE, EarlyView.
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley   +1 more source

Reconfiguring Fresh Produce Supply Chains in Response to Drought Risk: Evidence From the U.S. Broccoli Market

open access: yesAgribusiness, EarlyView.
ABSTRACT Drought is among the most severe and persistent threats to food supply chains, and relocating production to less drought‐prone regions offers a strategy to reduce this risk. This is particularly relevant for fresh vegetables, which are highly water‐intensive, yet drought‐driven reconfiguration strategies remain understudied.
Bingyan Dai   +2 more
wiley   +1 more source

Consumer Demand and Market Response to Added Sugar Labeling: Evidence From the Updated Nutrition Facts Panel

open access: yesAgribusiness, EarlyView.
ABSTRACT This paper examines how mandatory disclosure of added sugar content on the updated U.S. Nutrition Facts Panel (NFP) affects consumer demand and market outcomes. Using NielsenIQ Retail Scanner Data (2015–2020) and a random coefficient discrete choice model, we estimate how added sugar labeling influences purchasing behavior in yogurt and cookie
Yuxiang Zhang, Yizao Liu
wiley   +1 more source

The potency of native postbiotics and paraprobiotics in modulating inflammation by affecting the gut–kidney axis

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Native postbiotics and paraprobiotics derived from Lactobacillus and Bifidobacterium strains were administered to dextran sulfate sodium–treated C57BL/6 mice to evaluate their impact on kidney inflammation via the gut–kidney axis. Histological analysis and quantitative polymerase chain reaction of autophagy‐related genes (atg5, atg7, atg12, atg13 ...
Fatemeh Haririzadeh Jouriani   +6 more
wiley   +1 more source

Revisiting Securidaca longipedunculata Seed Oil: Applying NMR and Mass Spectroscopy to Confirm the Presence of 2‐Acetyl‐1,3‐Diacyl–sn‐Glycerols and Conjugated Hydroxydienoic Fatty Acids

open access: yesJournal of the American Oil Chemists' Society, EarlyView.
The manuscript confirms and expands on previous reports concerning the presence of unusual conjugated hydroxydienoic fatty acids and acetyl‐TAG in the seed oil of Securidaca longipedunculata. The location of acetate only at sn‐2 of TAG was conclusively shown by high resolution NMR and hydroxy seed fatty acids are characterized.
Mark A. Smith   +2 more
wiley   +1 more source

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