Chemical Proteomics Identifies Ketogenesis‐Mediated Cysteine Modifications Regulating Redox Function
Herein, we report ketone body induce cysteine modifications beyond lysine acylation, as revealed by integrating chemical proteomics with open‐search methods. Among the modifications, cysteine crotonation (Ccr) was chemically validated by endogenous peptide‐based co‐elution assays.
Yuan‐Fei Zhou +8 more
wiley +2 more sources
Multi-omics analysis provides insights into mechanisms of intestinal fungi adaptation to dietary carbohydrates. [PDF]
Li J +6 more
europepmc +1 more source
An 18‐month HFD successfully established a translational Macaca fascicularis model replicating key metabolic disorders (MASH, diabetes, cardiac hypertrophy). MASH was determined by liver biopsy histology, the presence steatosis, inflammatory infiltration, hepatocytic ballooning, and fibrosis were considered as MASH; diabetes was diagnosed according to ...
Hongyi Chen +12 more
wiley +1 more source
Dietary carbohydrates alter immune-modulatory functionalities and DNA inversions in Bacteroides thetaiotaomicron. [PDF]
Gal-Mandelbaum N +8 more
europepmc +1 more source
Glycemic Index (GI) Values for Major Sources of Dietary Carbohydrates in Iran. [PDF]
Kazemi F +8 more
europepmc +1 more source
Establishment of a novel cynomolgus monkey model of hyperuricemia
We established a novel hyperuricemia model in cynomolgus monkeys (A) via oral administration of potassium oxonate, hydrochlorothiazide, and adenine mixed in fruits and vegetables. This model (B) targets uric acid synthesis and enzymatic degradation, and (C) regulates renal and intestinal excretion, thereby stably elevating serum uric acid and serving ...
Ji‐Wei Wang +12 more
wiley +1 more source
The association between hypertension and different types of dietary carbohydrates. [PDF]
Rafieipour A +13 more
europepmc +1 more source
Dietary carbohydrates modulate metabolic and β-cell adaptation to high-fat diet-induced obesity. [PDF]
Her TK +5 more
europepmc +1 more source
The increasing prevalence of dementia and related neurodegenerative diseases—including Alzheimer's disease, Parkinson's disease, multiple sclerosis, and amyotrophic lateral sclerosis—poses a growing public health challenge. These conditions have traditionally been studied as isolated central nervous system disorders, but emerging evidence points to ...
Osayd Zohud +3 more
wiley +1 more source
A meta-analysis: dietary carbohydrates do not increase body fat or fasted insulin and glucose in cats. [PDF]
Godfrey H, Ellis JL, Verbrugghe A.
europepmc +1 more source

