Results 111 to 120 of about 4,412,013 (324)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

The Computational Diet: A Review of Computational Methods Across Diet, Microbiome, and Health. [PDF]

open access: yes, 2020
Food and human health are inextricably linked. As such, revolutionary impacts on health have been derived from advances in the production and distribution of food relating to food safety and fortification with micronutrients. During the past two decades,
Eetemadi, Ameen   +5 more
core  

Nutritional and Phytochemical Content of High-Protein Crops [PDF]

open access: yes, 2016
The authors acknowledge support from the Scottish Government’s Rural and Environment Science and Analytical Services Division (RESAS) via their strategic research and partnership programs.Peer ...
Cantlay, Louise   +7 more
core   +2 more sources

Fatty Acids Composition of Vegetable Oils and Its Contribution to Dietary Energy Intake and Dependence of Cardiovascular Mortality on Dietary Intake of Fatty Acids

open access: yesInternational Journal of Molecular Sciences, 2015
Characterizations of fatty acids composition in % of total methylester of fatty acids (FAMEs) of fourteen vegetable oils—safflower, grape, silybum marianum, hemp, sunflower, wheat germ, pumpkin seed, sesame, rice bran, almond, rapeseed, peanut, olive ...
Jana Orsavová   +4 more
semanticscholar   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Dietary specialization depending on ecological context and sexual differences in Asiatic black bears.

open access: yesPLoS ONE, 2019
The food habits of the Asiatic black bear (Ursus thibetanus) are well studied, but there is a little evidence of dietary specialization-that is, when individuals use a narrower set of resources compared to the population as a whole.
Tomoki Mori   +2 more
doaj   +1 more source

Utilizing a low-carbohydrate/high-protein diet to improve metabolic health in individuals with spinal cord injury (DISH): study protocol for a randomized controlled trial

open access: yesTrials, 2019
Background Metabolic disorders (e.g., impaired glucose tolerance, insulin resistance, and type 2 diabetes) are more prevalent in people with spinal cord injury (SCI) than able-bodied individuals.
Ceren Yarar-Fisher   +5 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Insect (Arthropoda: Insecta) Composition in the Diet of Ornate Box Turtles (Terrapene ornata ornata) in Two Western Illinois Sand Prairies, with a New State Record for Cyclocephala (Coleoptera: Scarabaeidae) [PDF]

open access: yes, 2018
A study of fecal samples collected over a two-year period from juvenile ornate box turtles (Terrapene ornata ornata Agassiz) revealed diets consisting of six orders of insects representing 19 families. Turtles were reared in captivity from eggs harvested
Lago, P. K.   +3 more
core   +3 more sources

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

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