Results 101 to 110 of about 2,474,608 (304)

Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane, Anna Capasso, Chiara Arpaia, Adele D’Amico, Emilio Albamonte, Federica Trucco, Maria Sframeli, Riccardo Masson, Francesca Magri, Luca Bello, Romina Venditti, Claudia Dosi, Michela Catteruccia, Michele Tosi, Claudio Bruno, Sonia Messina, Giacomo Comi, Elena Pegoraro, Valeria A. Sansone, Eugenio Mercuri   +19 more
wiley   +1 more source

The role of dietary antigen in the aetiology of post weaning diarrhoea [PDF]

, 1983
Experiments were undertaken to investigate whether a hypersensitivity response to dietary antigen might be a predisposing factor in the aetiology of post weaning diarrhoea. The results indicated that: 1.
Stokes, C.R., Newby, T.J., Hampson, D., Miller, B., Bourne, F.J.   +4 more
core  

Use of probabilistic exposure models in the assessment of dietary exposure to chemicals

Food Additives & Contaminants: Part A
This paper provides an introduction and overview of the use of probabilistic exposure assessments (PEAs) to characterize exposures to chemicals from the diet. The paper presents: 1) the concepts of uncertainty and variability with regard to dietary exposures; 2) the risk management needs that drive the use of probabilistic models; 3) the history of the
Greg M, Paoli, Emma, Hartnett, Paul S, Price   +2 more
openaire   +2 more sources

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source

Dietary Exposure to Food Contaminants of Pregnant Women in Northern Spain and Possible Effects on Fetal Anthropometric Parameters

Toxics
A considerable number of organizations are working to improve food safety, with particular attention to vulnerable groups such as pregnant women due to the important influence of diet on fetal development.
Daniel Hinojosa-Nogueira, José Ramón Bahamonde, Marta Aguilera-Nieto, Beatriz Navajas-Porras, Verónica González-Vigil, José Ángel Rufián-Henares, Silvia Pastoriza de la Cueva   +6 more
doaj   +1 more source

Associations of Lifestyle‐Related Factors and Psoriatic Arthritis Disease Activity: The Dutch South West Psoriatic Arthritis Study

Arthritis Care &Research, EarlyView.
Objective This study aims to investigate lifestyle‐related factors in patients with psoriatic arthritis (PsA) and their association with disease activity measurements. Methods This multicenter cohort included 938 patients who were newly diagnosed with PsA between 2013 and 2023.
Batoul Hojeij, Ilja Tchetverikov, Marc R. Kok, Marijn Vis, Yvonne Goekoop‐Ruiterman, Jessica Bijsterbosch, Paul Baudoin, Reinhard Bos, Jos H. van der Kaap, Petra Kok, Lindy‐Anne Korswagen, Jolanda J. Luime   +11 more
wiley   +1 more source

Acrylamide Intake in Senior Center Canteens: A Total Exposure Assessment Applying the Duplicate Diet Approach

Foods
This study conducted a total acrylamide exposure assessment through the daily diet in two Spanish senior centers using the duplicate diet method. Among foods regulated in Europe, only instant coffee provided at senior center 1 (2831 µg/kg) exceeded the ...
Marta Mesias, Lucía González-Mulero, Francisco J. Morales, Cristina Delgado-Andrade   +3 more
doaj   +1 more source

The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort

Arthritis Care &Research, EarlyView.
Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo, Ashish P. Balar, Aidan K. Strother, Subhash Kulkarni, Michael Hughes, Brian Skaug, Maureen D. Mayes, Shervin Assassi, Ali Y. Ayla, Zsuzsanna H. McMahan   +9 more
wiley   +1 more source

Statement on tolerable weekly intake for cadmium

EFSA Journal, 2011
The Panel on Contaminants in the Food Chain of the European Food Safety Authority (CONTAM Panel) was asked by the European Commission to confirm whether the current tolerable weekly intake (TWI) of 2.5 µg/kg body weight (b.w.) for cadmium is still ...
EFSA Panel on Contaminants in the Food Chain (CONTAM)
doaj   +1 more source