Results 181 to 190 of about 8,470,846 (303)

Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network

Advanced Science, EarlyView.
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt, Nico Kirsch, Aileen Kerfin, Lars P. Lunding, Dominic Ferber, Hannes Buthmann, Ilka Schreier, Carlotta Bosio, Ann‐Kathrin Dobbelstein, Anna Klawonn, Rebecca C. Coll, Lena Bauernhofer, Sandro Keller, Matthias Geyer, Michael Wegmann, Andra B. Schromm, Günther Weindl   +16 more
wiley   +1 more source

Protective and pathogenic dietary factors in bronchitis: Insights from Mendelian randomization. [PDF]

Medicine (Baltimore)
Wang J, Du Z, Lu Z, Yang T.
europepmc   +1 more source

A Comprehensive Microbial Gene Catalog of the Human Airway Microbiome Across Anatomical Sites and Geographic Regions

Advanced Science, EarlyView.
An integrated Human Airway Microbiome Gene Catalog (iHAMGC) is constructed from 12,273 metagenomic airway samples, providing a high‐resolution reference of respiratory microbial genes. The catalog enables systematic exploration of taxonomic and functional variation across airway niches and geographic regions, revealing site‐specific and region ...
Qing Zhang, Dashu Li, Bo Liu, Yue Zhang, Min Li, Ruochun Guo, Yawen Ni, Shibin Chen, Biao Ni, Lijie Qiu, Guorui Xing, He Dong, Qiulong Yan, Shenghui Li, Xiaohui Zou, Bin Cao   +15 more
wiley   +1 more source

Correction to "Causal Associations Between Dietary Factors and Uterine Inflammatory Diseases: A Mendelian Randomization Study". [PDF]

Food Sci Nutr
europepmc   +1 more source

Mediating Effects of Lipid Biomarkers and Sex-Specific Moderation on the Associations Between Anthropometric and Dietary Factors With Insulin Resistance. [PDF]

J Obes
Saha BUF, Navti LK, Teta I, Bey FY, Nantia EA, Bonglavnyuy TC, Sobngwi E.   +6 more
europepmc   +1 more source

Dietary factors and postprandial lipaemia [PDF]

British Journal of Nutrition, 1998
openaire   +3 more sources

Microprotein MP104 Promotes Malignant Progression of Colorectal Cancer Through Regulating Protein Translation

Advanced Science, EarlyView.
A previously unrecognized microprotein, MP104, encoded by ZEB1‐AS1, emerges as a critical driver of colorectal cancer progression. MP104 links ubiquitin‐mediated protein degradation with translational reprogramming via the UBE2O–AMPKα2–mTOR–EIF4B axis, revealing an unrecognized layer of oncogenic regulation.
Fang Chen, Miao Wang, Hongmei Yong, Jin Ding, Shiping Xu, Qirui Ge, Yan Wang, Lei Zhang, Qianqian Xiao, Benli Li, Li Lin, Sufang Chu, Qianqing Wang, Jin Bai, Pingfu Hou   +14 more
wiley   +1 more source

Associations between demographic, clinical and dietary factors and flares in inflammatory bowel disease: the PRognostic effect of Environmental factors in Crohn's and Colitis (PREdiCCt) prospective cohort study. [PDF]

Gut
Constantine-Cooke N, Gros B, Plevris N, Williams LJ, Jones GR, Kyle J, Kennedy NA, Velasco-Pardo V, Rudge A, Alexander D, Anderson CA, Brusco de Freitas M, Derr LM, Derikx LA, Gilchrist S, Henderson P, Horgan GW, Irving P, Lamb CA, Jostins-Dean L, Lindsay JO, MacDonald J, Mowat C, Murray C, Parkes M, Siakavellas SI, Vallejos CA, Gaya DR, Rhodes JM, Johnstone AM, Weir CJ, Lees CW, PREdiCCt study group.   +32 more
europepmc   +1 more source

Chemoselective Metabolomics via a Modular Reactivity‐Encoding Platform

Advanced Science, EarlyView.
Conventional LC–MS underrepresents numerous metabolites due to heterogeneous ionization efficiencies and matrix interference. Here, we introduce a modular reactivity‐encoding platform (MREP) comprising four alkyne‐tagged probes that selectively derivatize key functional groups, followed by unified click‐chemistry capture to eliminate matrix components ...
Xin Tao, Cang‐Man Zhang, Ru‐Jie Yang, Min Ren, Zhuo‐Ling Zhong, Kang‐Hui Wang, Rui‐Xue Hu, Jia‐Yue Liu, Jun‐Yi Zhou, Hou‐Kai Li, Jian‐Bo Wan   +10 more
wiley   +1 more source

Spicy food intake and dietary factors shape the gut microbiome and metabolism of mucin and short-chain fatty acids in healthy adults. [PDF]

Sci Rep
Min U, Kim J, Kim J, Jin H, Oh H, Ahn S, Shin H, Lee W.   +7 more
europepmc   +1 more source