Results 211 to 220 of about 1,664,645 (330)

Dietary fat differentially modulates the response of bone marrow-derived macrophages to TLR4 and NOD2 agonists. [PDF]

open access: yesInnate Immun, 2023
Shehat MG   +4 more
europepmc   +1 more source

Type 2 Diabetes‐Associated Phenylacetylglutamine Induces Deleterious Inflammation Cycle in Myeloid Cells through β2 Adrenergic Receptors and Impedes Wound Healing

open access: yesAdvanced Science, EarlyView.
The microbiota‐derived metabolite phenylacetylglutamine (PAGln) is elevated in type 2 diabetes and tightly associated with poor healing in both diabetic and non‐diabetic human patients. PAGln promotes mouse inflammation and impairs healing through a transmissible β2‐adrenergic receptor–mediated trained‐immunity loop.
Lu Huang   +12 more
wiley   +1 more source

Metabolomics-Based Biomarker for Dietary Fat and Associations with Chronic Disease Risk in Postmenopausal Women. [PDF]

open access: yesJ Nutr, 2023
Prentice RL   +20 more
europepmc   +1 more source

Quantitative effects of dietary fat on serum cholesterol in man.

open access: yesAmerican Journal of Clinical Nutrition, 1965
D. Hegsted   +3 more
semanticscholar   +1 more source

Hepatic KLF9 Deficiency Inhibits Dehydroepiandrosterone (DHEA)‐Induced Polycystic Ovary Syndrome via Liver‐Ovary Axis

open access: yesAdvanced Science, EarlyView.
The study shows that liver is a previously unrecognized extraovarian organ that plays a key role about androgen homeostasis in the development of DHEA‐induced PCOS. DHEA is the most common precursor of active androgen, such as DHT, and KLF9 is required for the conversion of DHEA to DHT and hepatic KLF9 might be a potential therapeutic target for PCOS ...
Jianli Song   +11 more
wiley   +1 more source

CREB coactivator CRTC1 in melanocortin-4 receptor-expressing cells regulate dietary fat intake. [PDF]

open access: yesFASEB Bioadv
Matsumura S   +7 more
europepmc   +1 more source

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