Results 271 to 280 of about 164,007 (344)
Obese gut‐microbiota derived lipopolysaccharides (LPS) induce bone marrow macrophage senescence and GCA secretion via activating TLR4/NF‐κB/MAPKs pathway. Clinically, obese patients are associated with higher serum GCA levels. Mice with depletion of GCA gene show resistance to skeletal deterioration caused by obesity and LPS‐induced chronic ...
Min Huang+16 more
wiley +1 more source
Proportions of macronutrients, including specific dietary fats, in prospective anti-Alzheimer's diet. [PDF]
Studnicki M, Dębski KJ, Stępkowski D.
europepmc +1 more source
Effect of Dietary and Injected Fat on the Fatty Acid Composition of Bovine Depot Fat and Milk Fat
S.B. Tove, R.D. Mochrie
openalex +1 more source
This study develops a human engineered heart tissue‐derived model of diabetic cardiomyopathy that accurately replicates the dynamic changes in the structural, contractile, and electrophysiological properties of the myocardium. Furthermore, this model is used to confirm the direct protective effects of empagliflozin on the heart through an SGLT2 off ...
Lin Cai+9 more
wiley +1 more source
The present study shows that macrophage WEE1 drives NF‐κB activation and inflammatory atherosclerosis by directly phosphorylating p65 at S536. This finding illustrates a macrophage‐specific WEE1‐p65 axis in regulating inflammatory atherosclerosis and points out new directions to broaden the clinical applications for WEE1 inhibitors in atherosclerosis ...
Zhuqi Huang+13 more
wiley +1 more source
Dietary Fats and Chronic Noncommunicable Diseases. [PDF]
Billingsley HE, Carbone S, Lavie CJ.
europepmc +1 more source
Influence of Dietary Fat and Choline on Serum and Egg Yolk Cholesterol in the Laying Chicken
N. J. Daghir, W.W. Marion, S.L. Balloun
openalex +1 more source
SUMOylation is a Translatable Target in Hypoxic MNPs Regulating Retinal Vasculopathy
During ischemic retinopathy/retinal vasculopathy, UBC9‐mediated SUMOylation in retinal macrophages enhances their pro‐angiogenic capacity via hypoxia‐induced SUMOylation of FUS at K327/K502. This modification suppresses FUS binding to the Vegfa mRNA 3’UTR, stabilizing transcripts and facilitating VEGFA production. Targeting UBC9 inhibition can serve as
Zheng Zhong+9 more
wiley +1 more source
Total Dietary Fats, Fatty Acids, and Omega-3/Omega-6 Ratio as Risk Factors of Breast Cancer in the Polish Population - a Case-Control Study. [PDF]
Dydjow-Bendek D, Zagoźdźon P.
europepmc +1 more source