Results 171 to 180 of about 2,290,705 (387)
Disorders in glucose and lipid metabolism are closely linked to chronic metabolic diseases, including obesity, non-alcoholic fatty liver, hyperlipidemia and diabetes.
DONG Hong-wang +4 more
doaj +1 more source
Germ‐free (GF) mice receiving fecal microbiota transplantation (FMT) reveal microbiota‐dependent effects on auditory aging. Integrated metagenomic, metabolomic and proteomic profiling maps gut–inner ear network and highlights 5‐hydroxytryptophan (5‐HTP) as a microbiota‐linked metabolic hub in age‐related hearing loss (ARHL).
Ting Yang +12 more
wiley +1 more source
In Situ Lipoprotein‐seeking Dye for in Vivo Real‐Time Imaging of Lipid Dysregulation Diseases
This study develops lipoprotein‐seeking NIR‐II dyes that specifically bind circulating lipoproteins. These dyes form ultra‐stable complexes with endogenous lipoprotein, enabling real‐time, high‐contrast imaging of fatty liver and atherosclerotic plaques. Tunable binding kinetics allow customized imaging windows.
Yijing Du +6 more
wiley +1 more source
Background: Sufficient dietary fiber consumption is associated with well-established health benefits, yet such intake is currently suboptimal globally. Thus, there is interest in developing strategies to improve dietary fiber intake. One such approach is
Victoria Norton +8 more
doaj +1 more source
The Impact of Dietary Fiber on Gut Microbiota in Host Health and Disease.
Kassem Makki +3 more
semanticscholar +1 more source
Schematic representation of ZIF‐8@OXA@inulin for cancer immunotherapy. Synthesis of ZIF‐8@OXA@inulin. Augmentation of pyroptosis, regulation of gut microbiota, and inhibition of NETs formation by ZIF‐8@OXA@inulin‐mediated comprehensive strategy for antitumor immune response. ABSTRACT Despite the potential of chemoimmunotherapy against colorectal cancer
Zhenhao Li +8 more
wiley +1 more source
HMGB2–RAD21 Axis Promotes Fibro/Adipogenic Progenitor Proliferation and Regulates Fat Infiltration
This study constructed the first developmental atlas of embryonic skeletal muscle fibro/adipogenic progenitors (FAPs) and identified an HMGB2+ FAPs subpopulation that regulates FAP pool size and muscle homeostasis. HMGB2 directly targets the RAD21 promoter, and its knockout significantly reduces FAP numbers, thereby lowering the potential for ...
Xian Tong +14 more
wiley +1 more source
Dietary Fat and Fiber Alter Rat Colonic Protein Kinase C Isozyme Expression
Laurie A. Davidson +5 more
openalex +1 more source
A redox‐active conductive carrier of tannic acid‐modified iron‐biochar with superior wettability is demonstrated to regulate direct electron transfer at the anaerobic biofilm‐carrier interface by enhancing the cytochrome c‐mediated pathway. For the first time, integrated evidence from spectroscopy, electrochemical analyses, and metatranscriptomics ...
Junli Tian +5 more
wiley +1 more source
繊維質とは,自然に放置しても分解されにくく,動物によっても消化されにくい成分のことを指す.本来,ヒトの消化酵素で消化されない繊維質は,生理的意義が低い非栄養素とされてきたが,難消化性の繊維質はヒトの健康維持に重要な役割を果たすことが次第に知られるようになった.食物繊維とは多糖類のひとつであるが,日本食品標準成分表2010では「ヒトの消化酵素で消化されない食品中の難消化性成分の総体」と定義されている.ヒトの炭水化物消化酵素であるアミラーゼは,デンプンを構成している糖分子のα結合を分解できるが,食物繊維を形成しているβ結合を分解する能力がない.従来,食物繊維はエネルギー源にならないと考えられていたが,実際は,消化されない食物繊維の一部が腸内細菌により発酵分解されて短鎖脂肪酸とガスになるため ...
openaire +2 more sources

