Results 171 to 180 of about 901,724 (295)

Ontogenetic Trophic Differentiation in the Amur Softshell Turtle (<i>Pelodiscus maackii</i>) From a Temperate Large-River System. [PDF]

Ecol Evol
Hou X.
europepmc   +1 more source

SLC25A4high Hepatocytes Enhance Lifestyle Intervention Response in MASLD by Recruiting Eating Macrophages

Advanced Science, EarlyView.
SLC25A4high hepatocytes drive metabolic‐associated steatotic liver disease (MASLD) remission by recruiting lipid‐eating macrophages. The hepatocyte Slc25a4/PANX1/ATP/P2ry12 axis mediates find‐me signaling that triggers macrophage recruitment and efferocytosis, while recruited macrophages secrete GDF15 to activate hepatocyte PPARα and promote fatty acid
Yiting Qian, Linying Lai, Yu Zhang, Yan Meng, Ziping Song, Baoyuan Huang, Guisheng Song, Bo Sun, Wenzhuo Yang   +8 more
wiley   +1 more source

Context‐Dependent Inverse Association of Glucose–Lipid Metabolic Status With Anemia: Evidence From Multinational Multicohort Analyses

Advanced Science, EarlyView.
Across six multinational cohorts, higher triglyceride–glucose index values are consistently associated with lower prevalent and incident anemia, despite their established adverse cardiometabolic significance. This inverse relationship varies across inflammatory, cardiovascular, and renal contexts, suggesting that glucose–lipid metabolic status carries ...
Guosong Jiang, Xinxing Wang, Lianfeng Xie, Wenna Ding, Yingyong Yin, Mei Yao, Zhibo Cui, Kaiqiang Tang, Lijie Zhong, Zhi Wang, Jia Wang, Lei Lei, Xiaoxiao Qu, Chi‐E. Qiu   +13 more
wiley   +1 more source

Metabarcoding reveals the dietary diversity and food web structure of spider functional guilds in a highly diverse subtropical forest. [PDF]

Oecologia
Chen J, Wang M, Luo A, Zhao Z, Zhang F, Chesters D, Shi X, Schuldt A, Zhu C.   +8 more
europepmc   +1 more source

Seasonal variations in diet composition, diet breadth and dietary overlap between three commercially important fish species within a flood-pulse system: The Tonle Sap Lake (Cambodia). [PDF]

PLoS One, 2018
Heng K, Chevalier M, Lek S, Laffaille P.
europepmc   +1 more source

Metabolic Signatures for Liver Cancer Diagnosis and Mechanistic Insights: A Large‐Scale, Multicenter Study

Advanced Science, EarlyView.
A large‐scale multicenter serum metabolomics study (13 centers, n = 2,149) identified a 9‐metabolite + AFP diagnostic signature for liver cancer (AUC = 0.93). Among the signature, nicotinamide (NAM) was validated as an oncometabolite: NAM enhances NAD+ synthesis, activating SIRT1 to deacetylate and stabilize HIF1α, thereby driving glycolysis, MAPK ...
Yongjie Xu, Jiachen Wang, Chunmeng Ding, Changfa Xia, Yunyong Liu, Yuanjie Zheng, Sheng Chang, Shaokai Zhang, Yutong He, Ruifang Sun, Yunfeng Xi, Yan Liu, Kun Qian, Wanqing Chen   +13 more
wiley   +1 more source

Trophic niche overlap between native and non-native fishes in central Anatolian lakes, Türkiye. [PDF]

J Fish Biol
Ramírez-García A, Korkmaz M, Pacheco JP, Tavşanoğlu ÜN, Pita-Zamudio MV, Acar V, Aznarez C, Metin M, Dede C, Yılmaz G, Ertuğrul S, Amorim CA, Çolak MA, Özgencil İK, Akyürek Z, Özkan K, Beklioğlu M, Jeppesen E.   +17 more
europepmc   +1 more source

NCOA4 Accelerates Abdominal Aortic Aneurysm Formation by Regulating Macrophage Activation and Ferroptosis via STAT1–CH25H Axis

Advanced Science, EarlyView.
Under pathological stimulation, NCOA4 in macrophages interacts with STAT1 to promote CH25H transcription. The subsequent increase in 25‐HC production activates macrophages, triggers inflammatory responses and ferroptosis, and accelerates the progression of AAA.
Zhinan Wu, Yuxuan Qian, Wenyi Xu, Fei Liao, Xueliang Liu, Xiao Kuang, Guqing Luo, Xinjie He, Lixian Jiang, Song Ding   +9 more
wiley   +1 more source

Associations of the exact-overlap Farm-to-Diet Coupling Index and production diversity with market dependence among smallholder farming households in Los Ríos, Ecuador: a cross-sectional study. [PDF]

Front Nutr
Zambrano-Villacres R, Cagua-Ordóñez J, Contreras-Moscol DJ, Andrade Mejia N, Gortaire-Díaz D, Simancas-Racines D.   +5 more
europepmc   +1 more source

Intermittent Fasting Reduces Taurine Availability and Promotes Antitumor Immunity Through PERK Attenuation‐Associated Paraptosis‐Like Cell Death in Colorectal Cancer

Advanced Science, EarlyView.
This study identifies reduced taurine availability as a mediator of intermittent fasting in colorectal cancer and shows that taurine interacts with GRP78 to maintain PERK abundance post‐transcriptionally. It further shows that taurine depletion destabilizes PERK, induces immunogenic paraptosis, remodels the tumor microenvironment toward a CD8+ T cell ...
Baohui Song, Sikei Kam, Jingyi Liu, Rui Lv, Xucheng Huo, Zhanghan Chen, Yuelun Dong, Shilun Cai, Bing Li, Ruobing Ren, Yunshi Zhong, Mingyan Cai   +11 more
wiley   +1 more source