Results 91 to 100 of about 539,261 (308)

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Healthy Japanese dietary pattern is associated with slower biological aging in older men: WASEDA’S health study

open access: yesFrontiers in Nutrition
Aging is the greatest risk factor for numerous diseases and mortality, and establishing geroprotective interventions targeting aging is required.
Takuji Kawamura   +22 more
doaj   +1 more source

IMPACTS OF EGYPTIAN SOCIO-ECONOMIC ENVIRONMENT ON DIETARY PATTERN AND ADEQUACY [PDF]

open access: yes
Health and nutrition status including dietary adequacy are basic components of the human development and indicators for welfare in a certain community.
Eid, Nafissa, Soliman, Ibrahim
core   +1 more source

A high-fat, high-glycaemic index, low-fibre dietary pattern is prospectively associated with type 2 diabetes in a British birth cohort [PDF]

open access: yes, 2016
The combined association of dietary fat, glycaemic index (GI) and fibre with type 2 diabetes has rarely been investigated. The objective was to examine the relationship between a high-fat, high-GI, low-fibre dietary pattern across adult life and type 2 ...
Ambrosini, GL   +3 more
core   +1 more source

Dietary patterns and colorectal cancer

open access: yesClinical Nutrition, 2017
Dietary pattern and lifestyle have been reported to be important risk factors in the development of colorectal cancer (CRC). However, the mechanism of action of dietary factors in CRC disease is unclear. The aim of this study is the examination of several dietary choices and their potential association with the risk of developing CRC.Dietary data was ...
Tayyem, Reema F.   +8 more
openaire   +4 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Dietary patterns are associated with calcium and vitamin D intake in an adult Mexican population

open access: yesNutrición Hospitalaria
Introduction: Nutrition research has traditionally promoted a nutrient-based approach; however, to evaluate population compliance with dietary recommendations, researchers have increasingly used dietary pattern analysis.
Edgar Denova-Gutiérrez   +8 more
doaj   +1 more source

A spatial analysis of dietary patterns in a large representative population in the north of The Netherlands – the Lifelines cohort study

open access: yesInternational Journal of Behavioral Nutrition and Physical Activity, 2017
Background Diet is an important modifiable risk factor for chronic diseases. In the search for effective strategies to improve dietary patterns in order to promote healthy ageing, new approaches considering contextual factors in public health medicine ...
Louise H. Dekker   +3 more
doaj   +1 more source

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Comparative metabolomics in primates reveals the effects of diet and gene regulatory variation on metabolic divergence. [PDF]

open access: yes, 2014
Human diets differ from those of non-human primates. Among few obvious differences, humans consume more meat than most non-human primates and regularly cook their food.
Blekhman, Ran   +5 more
core   +2 more sources

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