Results 131 to 140 of about 539,261 (308)
Effects of breed type, silage harvest date and pattern of offering concentrates on intake, performance and carcass traits of finishing steers [PDF]
peer-reviewedThe objective of this experiment was to investigate the effects and interactions of breed type, silage harvest date and pattern of offering concentrates on intake, performance and carcass traits of finishing steers.
Cummins, B. +3 more
core
Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati +10 more
wiley +1 more source
Dietary Adaptations and Intra- and Interspecific Variation in Dental Occlusal Shape in Hominin and Non-hominin Primates [PDF]
Dental morphology and tooth shape have been used to recreate the dietary adaptations for extinct species, and thus dental variation can provide information on the relationship between fossil species and their paleoenvironments.
O\u27Neill, Kelsey
core +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang +10 more
wiley +1 more source
Ahmed Gharib Khamis,1 Akwilina Wendelin Mwanri,2 Mbazi Senkoro,3 Katharina Kreppel,4,5 Bassirou Bonfoh,6 Sayoki Godfrey Mfinanga,3 Gideon Kwesigabo1 1Department of Epidemiology and Biostatistics, Muhimbili University of Health and Allied Sciences, Dar-es-
Khamis AG +6 more
doaj
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Mediterranean diet and cancer: epidemiological evidence and mechanism of selected aspects [PDF]
Background: Populations living in the area of the Mediterranean Sea suffered by decreased incidence of cancer compared with those living in the regions of northern Europe and US countries, attributed to healthier dietary habits.
Basile, F +9 more
core
Objective Body mass index (BMI), glomerular filtration rate (GFR), and pretreatment urate levels have been reported to influence the urate‐lowering response to allopurinol. We investigated whether the fractional excretion of uric acid (FEUA) also modulates this response and relates to oxypurinol concentrations.
Pascal Richette +13 more
wiley +1 more source

